Details
Stereochemistry | RACEMIC |
Molecular Formula | C17H14Cl2N2O2 |
Molecular Weight | 349.211 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=CC2=C(NC(=O)CN3CCOC23C4=C(Cl)C=CC=C4)C=C1
InChI
InChIKey=ZIXNZOBDFKSQTC-UHFFFAOYSA-N
InChI=1S/C17H14Cl2N2O2/c18-11-5-6-15-13(9-11)17(12-3-1-2-4-14(12)19)21(7-8-23-17)10-16(22)20-15/h1-6,9H,7-8,10H2,(H,20,22)
CNS Activity
Originator
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
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Target ID: CHEMBL2109243 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
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Primary | OLCADIL Approved UseEmotional disorders such as anxiety, tension, restlessness; sleep disorders such as difficulty falling asleep, insomnia and early awakening; pre-medication prior to surgery. Launch Date2013 |
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Primary | OLCADIL Approved UseEmotional disorders such as anxiety, tension, restlessness; sleep disorders such as difficulty falling asleep, insomnia and early awakening; pre-medication prior to surgery. Launch Date2013 |
PubMed
Title | Date | PubMed |
---|---|---|
[A case of amoxapine-induced tardive dystonia successfully treated with a low dose anti-cholinergic agent]. | 2000 Apr |
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Selective and potent inhibitors of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) that metabolizes neurosteroids derived from progesterone. | 2003 Feb 1 |
Patents
Sample Use Guides
Symptoms of mild to moderate severity: a tablet (2 mg) and a half to three tablets per day, divided into two administrations; Symptoms of moderately severe to severe: 3 to 4 tablets per day divided in two administrations.The optimal therapeutic dosage should be determined individually by progressive adjustment. max recommended dose: 6 tablets (12 mg)/day.
Route of Administration:
Oral
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Classification Tree | Code System | Code | ||
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DEA NO. |
2753
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WHO-ATC |
N05BA22
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NCI_THESAURUS |
C28197
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WHO-VATC |
QN05BA22
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CHEMBL2107254
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m3674
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2816
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C79883
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SUB06781MIG
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100000084056
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CLOXAZOLAM
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24166-13-0
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721
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21311
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DB01553
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C005522
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GYL649Z0HY
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DTXSID0022854
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3400
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ACTIVE MOIETY