.ALPHA.-PYRROLIDINOPROPIOPHENONE(HYDROCHLORIDE)

Details

Stereochemistry	RACEMIC
Molecular Formula	C13H17NO.ClH
Molecular Weight	239.741
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of .ALPHA.-PYRROLIDINOPROPIOPHENONE(HYDROCHLORIDE)

SMILES

Cl.CC(N1CCCC1)C(=O)C2=CC=CC=C2

InChI

InChIKey=VQCZQKJXTMYEQV-UHFFFAOYSA-N

InChI=1S/C13H17NO.ClH/c1-11(14-9-5-6-10-14)13(15)12-7-3-2-4-8-12;/h2-4,7-8,11H,5-6,9-10H2,1H3;1H

HIDE SMILES / InChI

Originator

Approval Year

Targets

Targets

Primary Target	Pharmacology	Potency
Serotonin 2a (5-HT2a) receptor 237	Antagonist 2,849	5.6 null [pKi]
Serotonin transporter 183	Inhibitor 8,504	188.0 µM [IC50]
Norepinephrine transporter 197	Inhibitor 8,504	0.305 µM [IC50]
Dopamine transporter 183	Inhibitor 8,504	0.54 µM [IC50]

PubMed

Show entries

Title	Date	PubMed
Metabolism of the new designer drug alpha-pyrrolidinopropiophenone (PPP) and the toxicological detection of PPP and 4'-methyl-alpha-pyrrolidinopropiophenone (MPPP) studied in rat urine using gas chromatography-mass spectrometry.	2003 Nov 5	14581066

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Patents

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Name

Type

Language

.ALPHA.-PPP HYDROCHLORIDE

Preferred Name

English

.ALPHA.-PYRROLIDINOPROPIOPHENONE(HYDROCHLORIDE)

Common Name

English

PROPIOPHENONE, 2-(1-PYRROLIDINYL)-, HYDROCHLORIDE

Systematic Name

English

1-PROPANONE, 1-PHENYL-2-(1-PYRROLIDINYL)-, HYDROCHLORIDE (1:1)

Systematic Name

English

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Code System

Code

Type

Description

FDA UNII

GR65F46FM8

PRIMARY

CAS

92040-10-3

PRIMARY

EPA CompTox

DTXSID201347643

PRIMARY

PUBCHEM

21114962

PRIMARY

MANUFACTURER PRODUCT INFORMATION

.ALPHA.-PYRROLIDINOPROPIOPHENONE(HYDROCHLORIDE)

PRIMARY

α-Pyrrolidinopropiophenone (hydrochloride) is an analog of the appetite suppressant diethylcathinone and is related to the designer drug 4?-methyl-α-pyrrolidinopropiophenone (MPPP). In male Wistar rats, it is metabolized to a variety of products, including cathinone, the main psychoactive alkaloid of kath (Catha edulis). α-Pyrrolidinopropiophenone (hydrochloride) is intended to be used for forensic applications.

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SUBSTANCE RECORD


					GR65F46FM8

.ALPHA.-PYRROLIDINOPROPIOPHENONE(HYDROCHLORIDE)