.ALPHA.-PYRROLIDINOPROPIOPHENONE(HYDROCHLORIDE)

Cl.CC(N1CCCC1)C(=O)C2=CC=CC=C2

InChIKey=VQCZQKJXTMYEQV-UHFFFAOYSA-N

InChI=1S/C13H17NO.ClH/c1-11(14-9-5-6-10-14)13(15)12-7-3-2-4-8-12;/h2-4,7-8,11H,5-6,9-10H2,1H3;1H

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Targets

Primary Target	Pharmacology	Potency
Serotonin 2a (5-HT2a) receptor 237 Target ID: CHEMBL224 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30845376	Antagonist 2849	5.6 null [pKi]
Serotonin transporter 183 Target ID: CHEMBL228 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27799294	Inhibitor 8504	188.0 µM [IC50]
Norepinephrine transporter 197 Target ID: CHEMBL222 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27799294	Inhibitor 8504	0.305 µM [IC50]
Dopamine transporter 183 Target ID: CHEMBL238 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27799294	Inhibitor 8504	0.54 µM [IC50]

PubMed

Title	Date	PubMed
Metabolism of the new designer drug alpha-pyrrolidinopropiophenone (PPP) and the toxicological detection of PPP and 4'-methyl-alpha-pyrrolidinopropiophenone (MPPP) studied in rat urine using gas chromatography-mass spectrometry.	2003-11-05	14581066

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:11:46 GMT 2025` Edited by `admin` on `Mon Mar 31 23:11:46 GMT 2025`
Record UNII	GR65F46FM8
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

.ALPHA.-PPP HYDROCHLORIDE

Preferred Name

English

.ALPHA.-PYRROLIDINOPROPIOPHENONE(HYDROCHLORIDE)

Common Name

English

PROPIOPHENONE, 2-(1-PYRROLIDINYL)-, HYDROCHLORIDE

Systematic Name

English

1-PROPANONE, 1-PHENYL-2-(1-PYRROLIDINYL)-, HYDROCHLORIDE (1:1)

Systematic Name

English

Code System Code Type Description

FDA UNII

GR65F46FM8