Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C27H40O6 |
| Molecular Weight | 460.6029 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 7 / 7 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12CC[C@](O)(C(=O)COC(=O)CC(C)(C)C)[C@@]1(C)C[C@H](O)[C@@]3([H])[C@@]2([H])CCC4=CC(=O)CC[C@]34C
InChI
InChIKey=FNFPHNZQOKBKHN-KAJVQRHHSA-N
InChI=1S/C27H40O6/c1-24(2,3)14-22(31)33-15-21(30)27(32)11-9-19-18-7-6-16-12-17(28)8-10-25(16,4)23(18)20(29)13-26(19,27)5/h12,18-20,23,29,32H,6-11,13-15H2,1-5H3/t18-,19-,20-,23+,25-,26-,27-/m0/s1
Approval Year
Cmax
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
258 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/2050835 |
20 mg single, oral dose: 20 mg route of administration: Oral experiment type: SINGLE co-administered: |
HYDROCORTISONE plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
AUC
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
1162 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/2050835 |
20 mg single, oral dose: 20 mg route of administration: Oral experiment type: SINGLE co-administered: |
HYDROCORTISONE plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
|
1175 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/2050835 |
20 mg single, intravenous dose: 20 mg route of administration: Intravenous experiment type: SINGLE co-administered: |
HYDROCORTISONE plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
T1/2
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
1.82 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/2050835 |
20 mg single, oral dose: 20 mg route of administration: Oral experiment type: SINGLE co-administered: |
HYDROCORTISONE plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
|
1.66 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/2050835 |
20 mg single, intravenous dose: 20 mg route of administration: Intravenous experiment type: SINGLE co-administered: |
HYDROCORTISONE plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
|
1.5 h |
unknown, oral |
HYDROCORTISONE plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
Funbound
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
10% |
unknown, oral |
HYDROCORTISONE plasma | Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
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FXJ67LWZ4S
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508-96-3
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DTXSID00198830
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208-090-5
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23424017
Created by
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SUBSTANCE RECORD
