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Details

Stereochemistry ACHIRAL
Molecular Formula C14H6Cl2F4N2O2
Molecular Weight 381.109
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TEFLUBENZURON

SMILES

FC1=CC=CC(F)=C1C(=O)NC(=O)NC2=C(F)C(Cl)=C(F)C(Cl)=C2

InChI

InChIKey=CJDWRQLODFKPEL-UHFFFAOYSA-N
InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)

HIDE SMILES / InChI

Description

Teflubenzuron is an insecticide which inhibits the biochemical synthesis of chitin. It controls all immature stages of the insects; the youngest larvae are the most susceptible and less teflubenzuron needs to be applied to control young larvae than older ones. The insecticidal activity of teflubenzuron results primarily from the ingestion of treated foliage; contact activity is less significant. The compound is also ovicidal by topical application. Teflubenzuron is used to control a wide range of insect pests and mites in fruit, vegetable, cereal and seed crops. It is also occasionally used to control sealice infestations in salmon.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
CALICIDE

PubMed

Sample Use Guides

In Vivo Use Guide
Teflubenzuron (Calicide) is effective for the treatment of farmed Atlantic salmon Salmo salar L. infested with sea lice Lepeophtheirus salmonis (Krøyer, 1838) at a dose of 10mg/kg body weight per day for 7 consecutive days
Route of Administration: Oral
In Vitro Use Guide
Teflubenzuron efficacy against Trichodina spp., was assessed using the concentrations of 30.0 or 50.0 mg/l for one hour exposure in tilapia, and the concentration of 30.0, 50.0 and 80.0 mg/l for one hour and 50 mg/l for two hours exposures in pacu. The drug effectiveness was observed against four identified Trichodina species: T. magna, T. heterodentata, T. compacta and T. centrostrigeata, with 87.9% parasite reduction with one hour exposure to 50.0 mg/l Teflubenzuron on O. niloticus and 96.1% with two hours exposure to 50.0 mg/l TFB on P. mesopotamicus.