Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C14H6Cl2F4N2O2 |
| Molecular Weight | 381.109 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
FC1=CC=CC(F)=C1C(=O)NC(=O)NC2=C(F)C(Cl)=C(F)C(Cl)=C2
InChI
InChIKey=CJDWRQLODFKPEL-UHFFFAOYSA-N
InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)
DescriptionCurator's Comment: Description was created based on several sources, including
http://www.fluoridealert.org/wp-content/pesticides/teflubenzuron.scotlandepa99.pdf | http://apps.sepa.org.uk/spripa/Pages/SubstanceInformation.aspx?pid=173
Curator's Comment: Description was created based on several sources, including
http://www.fluoridealert.org/wp-content/pesticides/teflubenzuron.scotlandepa99.pdf | http://apps.sepa.org.uk/spripa/Pages/SubstanceInformation.aspx?pid=173
Teflubenzuron is an insecticide which inhibits the biochemical synthesis of chitin. It controls all immature stages of the insects; the youngest larvae are the most susceptible and less teflubenzuron needs to be applied to control young larvae than older ones. The insecticidal activity of teflubenzuron results primarily from the ingestion of treated foliage; contact activity is less significant. The compound is also ovicidal by topical application. Teflubenzuron is used to control a wide range of insect pests and mites in fruit, vegetable, cereal and seed crops. It is also occasionally used to control sealice infestations in salmon.
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Curative | CALICIDE Approved UseCalicide (active ingredient Teflubenzuron) is a new in-feed sea lice treatment chemical for use by the marine salmon farming industry. Launch Date1997 |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Transformation of the insecticide teflubenzuron by microorganisms. | 2001 Sep |
|
| Clinical efficacy of teflubenzuron (Calicide) for the treatment of Lepeophtheirus salmonis infestations of farmed Atlantic salmon Salmo salar at low water temperatures. | 2002 Aug 29 |
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| New developments in insecticide resistance in the glasshouse whitefly (Trialeurodes vaporariorum) and the two-spotted spider mite (Tetranychus urticae) in the UK. | 2002 Feb |
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| Field trials in Norway with SLICE (0.2% emamectin benzoate) for the oral treatment of sea lice infestation in farmed Atlantic salmon Salmo salar. | 2002 Jun 21 |
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| Age-dependent response to insecticides and enzymatic variation in susceptible and resistant codling moth larvae. | 2002 Oct |
|
| Novaluron (Rimon), a novel IGR: potency and cross-resistance. | 2003 Dec |
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| Determination of seventeen polar/thermolabile pesticides in apples and apricots by liquid chromatography/mass spectrometry. | 2003 May-Jun |
|
| Influence of a short exposure to teflubenzuron residues on the predation of thrips by Iphiseius degenerans (Acari: Phytoseiidae) and Orius laevigatus (Hemiptera: Anthocoridae). | 2003 Nov |
|
| Toxicological efficacy of some indigenous dill compounds against the flesh fly, Parasarcophaga dux Thomson. | 2004 Apr |
|
| Persistence and residual activity of an organophosphate, pirimiphos-methyl, and three IGRs, hexaflumuron, teflubenzuron and pyriproxyfen, against the cowpea weevil, Callosobruchus maculatus (Coleoptera: Bruchidae). | 2004 Jan |
|
| Effects of teflubenzuron on sediment processing by members of the Capitella species-complex. | 2006 Jan |
|
| Laboratory evaluation of five chitin synthesis inhibitors against the colorado potato beetle, Leptinotarsa decemlineata. | 2007 |
|
| Compatibility of Verticillium lecani (Zimm.) with several pesticides. | 2007 |
|
| Determination of benzoylurea insecticide residues in tomatoes by high-performance liquid chromatography with ultraviolet-diode array and atmospheric pressure chemical ionization-mass spectrometry detection. | 2007 Sep-Oct |
|
| Side effects of teflubenzuron and chlorfenapyr in Eriopis connexa eggs (Coleoptera: Coccinellidae). | 2009 |
|
| [Determination of benzoylurea and bishydrazide pesticide residues in vegetables by ultra performance liquid chromatography-tandem mass spectrometry with matrix solid phase dispersion]. | 2010 Apr |
|
| N-Benzoyl-N'-phenyl-urea. | 2010 Jan 20 |
|
| The effect of chitin metabolic effectors on the population increase of stored product mites. | 2010 Oct |
|
| Field evaluation of pyriproxyfen and spinosad mixture for the control of insecticide resistant Aedes aegypti in Martinique (French West Indies). | 2010 Sep 16 |
Sample Use Guides
Teflubenzuron (Calicide) is effective for the treatment of farmed Atlantic salmon Salmo salar L. infested with sea lice Lepeophtheirus salmonis (Krøyer, 1838) at a dose of 10mg/kg body weight per day for 7 consecutive days
Route of Administration:
Oral
Teflubenzuron efficacy against Trichodina spp., was assessed using the concentrations of 30.0 or 50.0 mg/l for one hour exposure in tilapia, and the concentration of 30.0, 50.0 and 80.0 mg/l for one hour and 50 mg/l for two hours exposures in pacu. The drug effectiveness was observed against four identified Trichodina species: T. magna, T. heterodentata, T. compacta and T. centrostrigeata, with 87.9% parasite reduction with one hour exposure to 50.0 mg/l Teflubenzuron on O. niloticus and 96.1% with two hours exposure to 50.0 mg/l TFB on P. mesopotamicus.
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QP53BC03
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EPA PESTICIDE CODE |
129048
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DTXSID6042440
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83121-18-0
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39387
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m10519
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367306
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SUB130601
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FS9P57VL74
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teflubenzuron
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SUBSTANCE RECORD
