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Details

Stereochemistry ACHIRAL
Molecular Formula C11H12O3
Molecular Weight 192.2112
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 5,6-DIMETHOXY-1-INDANONE

SMILES

COC1=CC2=C(C=C1OC)C(=O)CC2

InChI

InChIKey=IHMQOBPGHZFGLC-UHFFFAOYSA-N
InChI=1S/C11H12O3/c1-13-10-5-7-3-4-9(12)8(7)6-11(10)14-2/h5-6H,3-4H2,1-2H3

HIDE SMILES / InChI
5,6-Dimethoxy-1-Indanone is used for the organic synthesis. It is an intermediate useful in the preparation of acetylcholinesterase inhibitor Donepezil. 5,6-Dimethoxy-1-Indanone derivatives displayed a potent suppression of the hepatitis C virus (HCV) replication and inhibition of bovine viral diarrhea virus RNA synthesis.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Dopamine D(3) receptor antagonists. 1. Synthesis and structure-activity relationships of 5,6-dimethoxy-N-alkyl- and N-alkylaryl-substituted 2-aminoindans.
2001 Dec 20
Synthesis of novel, potentially biologically active dibenzosuberone derivatives.
2005 Dec 31
Simple and regioselective bromination of 5,6-disubstituted-indan-1-ones with Br2 under acidic and basic conditions.
2007 Jan 29
Photochemical synthesis of substituted indan-1-ones related to donepezil.
2008 May
Methyl 5,6-dimeth-oxy-1H-indole-2-carboxyl-ate.
2009 Sep 5
(2E)-2-Benzyl-idene-5,6-dimethoxy-indan-1-one.
2010 Sep 11
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
5,6-DIMETHOXY-1-INDANONE
Systematic Name English
1H-INDEN-1-ONE, 2,3-DIHYDRO-5,6-DIMETHOXY-
Systematic Name English
5,6-DIMETHOXY-2,3-DIHYDRO-1H-INDEN-1-ONE
Systematic Name English
DONEPEZIL HYDROCHLORIDE MONOHYDRATE IMPURITY B [EP IMPURITY]
Common Name English
DONEPEZIL HYDROCHLORIDE IMPURITY B [EP IMPURITY]
Common Name English
NSC-401450
Code English
5,6-DIMETHOXYINDANE-1-ONE
Systematic Name English
Code System Code Type Description
FDA UNII
F805RZI8GO
Created by admin on Sat Dec 16 08:49:33 GMT 2023 , Edited by admin on Sat Dec 16 08:49:33 GMT 2023
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EPA CompTox
DTXSID9057680
Created by admin on Sat Dec 16 08:49:33 GMT 2023 , Edited by admin on Sat Dec 16 08:49:33 GMT 2023
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NSC
401450
Created by admin on Sat Dec 16 08:49:33 GMT 2023 , Edited by admin on Sat Dec 16 08:49:33 GMT 2023
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PUBCHEM
75018
Created by admin on Sat Dec 16 08:49:33 GMT 2023 , Edited by admin on Sat Dec 16 08:49:33 GMT 2023
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CAS
2107-69-9
Created by admin on Sat Dec 16 08:49:33 GMT 2023 , Edited by admin on Sat Dec 16 08:49:33 GMT 2023
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ECHA (EC/EINECS)
218-287-8
Created by admin on Sat Dec 16 08:49:33 GMT 2023 , Edited by admin on Sat Dec 16 08:49:33 GMT 2023
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