Details
Stereochemistry | ACHIRAL |
Molecular Formula | C11H12O3 |
Molecular Weight | 192.2112 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC2=C(C=C1OC)C(=O)CC2
InChI
InChIKey=IHMQOBPGHZFGLC-UHFFFAOYSA-N
InChI=1S/C11H12O3/c1-13-10-5-7-3-4-9(12)8(7)6-11(10)14-2/h5-6H,3-4H2,1-2H3
5,6-Dimethoxy-1-Indanone is used for the organic synthesis. It is an intermediate useful in the preparation of acetylcholinesterase inhibitor Donepezil. 5,6-Dimethoxy-1-Indanone derivatives displayed a potent suppression of the hepatitis C virus (HCV) replication and inhibition of bovine viral diarrhea virus RNA synthesis.
Approval Year
PubMed
Title | Date | PubMed |
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Dopamine D(3) receptor antagonists. 1. Synthesis and structure-activity relationships of 5,6-dimethoxy-N-alkyl- and N-alkylaryl-substituted 2-aminoindans. | 2001 Dec 20 |
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Synthesis of novel, potentially biologically active dibenzosuberone derivatives. | 2005 Dec 31 |
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Simple and regioselective bromination of 5,6-disubstituted-indan-1-ones with Br2 under acidic and basic conditions. | 2007 Jan 29 |
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Photochemical synthesis of substituted indan-1-ones related to donepezil. | 2008 May |
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Methyl 5,6-dimeth-oxy-1H-indole-2-carboxyl-ate. | 2009 Sep 5 |
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(2E)-2-Benzyl-idene-5,6-dimethoxy-indan-1-one. | 2010 Sep 11 |
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218-287-8
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SUBSTANCE RECORD