Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C16H21N3O2 |
| Molecular Weight | 287.3568 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)CCC1=CNC2=C1C=C(C[C@@H]3COC(=O)N3)C=C2
InChI
InChIKey=ULSDMUVEXKOYBU-CYBMUJFWSA-N
InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m1/s1
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| The cost effectiveness of stratified care in the management of migraine. | 2001 |
|
| New abortive agents for the treatment of migraine. | 2001 |
|
| Sumatriptan, 5-HT(1D) receptors and obsessive-compulsive disorder. | 2001 Apr |
|
| A systematic review of the use of triptans in acute migraine. | 2001 Feb |
|
| What is the optimal strategy for managing acute migraine headaches? | 2001 Feb |
|
| Molecular cloning, pharmacological properties and tissue distribution of the porcine 5-HT(1B) receptor. | 2001 Jul |
|
| Current options for the prevention and treatment of migraine. | 2001 Jun |
|
| Acute treatment of migraine and the role of triptans. | 2001 Mar |
|
| Zolmitriptan versus sumatriptan comparison trial. | 2001 Mar |
|
| 4991W93 inhibits release of calcitonin gene-related peptide in the cat but only at doses with 5HT(1B/1D) receptor agonist activity? | 2001 Mar |
|
| Decreased sensitivity of 5-HT(1D) receptors in melancholic depression. | 2001 May |
|
| Zolmitriptan versus sumatriptan for the acute oral treatment of migraine: a randomized, double-blind, international study. | 2001 May |
|
| [Cost effectiveness of treatment with triptanes in Spain]. | 2001 Nov 16-30 |
|
| Triptans in the treatment of basilar migraine and migraine with prolonged aura. | 2001 Nov-Dec |
|
| Comparison of rizatriptan and other triptans on stringent measures of efficacy. | 2001 Oct 23 |
|
| Dexamethasone decreases migraine recurrence observed after treatment with a triptan combined with a nonsteroidal anti-inflammatory drug. | 2001 Sep |
|
| Effect of rizatriptan and other triptans on the nausea symptom of migraine: a post hoc analysis. | 2001 Sep |
|
| Triptans are all different. | 2001 Sep |
|
| [The problems of migraine headache treatment]. | 2002 |
|
| An introduction to migraine: from ancient treatment to functional pharmacology and antimigraine therapy. | 2002 |
|
| Spotlight on rizatriptan in migraine. | 2002 |
|
| Cost-effectiveness analysis of stratified versus stepped care strategies for acute treatment of migraine: The Disability in Strategies for Care (DISC) Study. | 2002 |
|
| Re: Zakrzewska JM. Cluster headache: review of the literature. Br J Oral Maxillofac Surg 2001; 39: 103-113. | 2002 Feb |
|
| [Migraine: a disease, not a symptom]. | 2002 Jan 1 |
|
| Simultaneous measurement of zolmitriptan and its major metabolites N-desmethylzolmitriptan and zolmitriptan N-oxide in human plasma by high-performance liquid chromatography with coulometric detection. | 2002 Jan 25 |
|
| [Splenic infarction associated with Zolmitriptan use]. | 2002 Mar |
|
| Pharmacological approaches to migraine. | 2003 |
|
| [Zolmitriptan-induced hepatotoxicity]. | 2003 Dec |
|
| In vitro metabolism of zolmitriptan in rat cytochromes induced with beta-naphthoflavone and the interaction between six drugs and zolmitriptan. | 2003 Dec 15 |
|
| Coprescription of triptans with potentially interacting medications: a cohort study involving 240,268 patients. | 2003 Jan |
|
| Meta-analysis of oral triptan therapy for migraine: number needed to treat and relative cost to achieve relief within 2 hours. | 2003 Jan-Feb |
|
| Zolmitriptan for treatment of migrainous vertigo: a pilot randomized placebo-controlled trial. | 2003 Mar 11 |
|
| [Highly selective beginning. Associated symptoms and side effects in retrospect]. | 2003 May 26 |
|
| Abnormal habituation of 'nociceptive' blink reflex in migraine--evidence for increased excitability of trigeminal nociception. | 2003 Oct |
|
| Clinical applications of new therapeutic deliveries in migraine. | 2003 Oct 28 |
|
| Zolmitriptan nasal spray: advances in migraine treatment. | 2003 Oct 28 |
|
| Patients with migraine prefer zolmitriptan orally disintegrating tablet to sumatriptan conventional oral tablet. | 2003 Sep |
|
| Effects of acute or chronic administration of anti-migraine drugs sumatriptan and zolmitriptan on serotonin synthesis in the rat brain. | 2004 Jan |
|
| Zolmitriptan (Zomig) nasal spray for migraine. | 2004 Jan 19 |
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F3YOE57701
Created by
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1727018
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139264-24-7
Created by
admin on Sat Dec 16 10:48:02 GMT 2023 , Edited by admin on Sat Dec 16 10:48:02 GMT 2023
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441240
Created by
admin on Sat Dec 16 10:48:02 GMT 2023 , Edited by admin on Sat Dec 16 10:48:02 GMT 2023
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SUBSTANCE RECORD
