Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C23H25N3O2 |
| Molecular Weight | 375.4635 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O=C1CC2=CC3=C(ON=C3CCC4CCN(CC5=CC=CC=C5)CC4)C=C2N1
InChI
InChIKey=MTCMTKNMZCPKLX-UHFFFAOYSA-N
InChI=1S/C23H25N3O2/c27-23-13-18-12-19-20(25-28-22(19)14-21(18)24-23)7-6-16-8-10-26(11-9-16)15-17-4-2-1-3-5-17/h1-5,12,14,16H,6-11,13,15H2,(H,24,27)
Icopezil (previously known as CP-118,954) was developed as a selective acetylcholinesterase inhibitor for the treatment of cognitive disorders. Phase II trials of icopezil were underway in Japan and in the USA for the treatment of patients with Alzheimer's disease. However, Pfizer has discontinued these studies.
Approval Year
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NCI_THESAURUS |
C47792
Created by
admin on Fri Dec 15 19:00:30 GMT 2023 , Edited by admin on Fri Dec 15 19:00:30 GMT 2023
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C99558
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145508-78-7
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172972
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100000083673
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DTXSID70932622
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7492
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CHEMBL359570
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SUB08108MIG
Created by
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ERZ60E6B7C
Created by
admin on Fri Dec 15 19:00:30 GMT 2023 , Edited by admin on Fri Dec 15 19:00:30 GMT 2023
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PRIMARY |
ACTIVE MOIETY
SALT/SOLVATE (PARENT)
