U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C24H29F3O6
Molecular Weight 470.4787
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 3
Charge 0

SHOW SMILES / InChI
Structure of FROXIPROST

SMILES

COC(=O)\C=C\C\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COC2=CC=CC(=C2)C(F)(F)F

InChI

InChIKey=REFZGTXXBBUTMJ-YDQNNXAVSA-N
InChI=1S/C24H29F3O6/c1-32-23(31)10-5-3-2-4-9-19-20(22(30)14-21(19)29)12-11-17(28)15-33-18-8-6-7-16(13-18)24(25,26)27/h2,4-8,10-13,17,19-22,28-30H,3,9,14-15H2,1H3/b4-2-,10-5+,12-11+/t17-,19-,20-,21+,22-/m1/s1

HIDE SMILES / InChI
PubMed

PubMed

TitleDatePubMed
Involvement of phosphatidylcholine hydrolysis by phospholipase C in prostaglandin F2alpha-induced 1,2-diacylglycerol formation in osteoblast-like MC3T3-E1 cells.
2004
Patents
Name Type Language
FROXIPROST
INN  
INN  
Official Name English
froxiprost [INN]
Common Name English
METHYL (2E,5Z)-7-((1R,2R,3R,5S)-3,5-DIHYDROXY-2-((E)-(3R)-3-HYDROXY-4-((.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-M-TOLYL)OXY)-1-BUTENYL)CYCLOPENTYL)-2,5-HEPTADIENOATE
Systematic Name English
FROXIPROST [JAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C78568
Created by admin on Fri Dec 15 16:37:27 GMT 2023 , Edited by admin on Fri Dec 15 16:37:27 GMT 2023
Code System Code Type Description
EVMPD
SUB07818MIG
Created by admin on Fri Dec 15 16:37:27 GMT 2023 , Edited by admin on Fri Dec 15 16:37:27 GMT 2023
PRIMARY
CAS
62559-74-4
Created by admin on Fri Dec 15 16:37:27 GMT 2023 , Edited by admin on Fri Dec 15 16:37:27 GMT 2023
PRIMARY
INN
5898
Created by admin on Fri Dec 15 16:37:27 GMT 2023 , Edited by admin on Fri Dec 15 16:37:27 GMT 2023
PRIMARY
SMS_ID
100000080468
Created by admin on Fri Dec 15 16:37:27 GMT 2023 , Edited by admin on Fri Dec 15 16:37:27 GMT 2023
PRIMARY
FDA UNII
EOS1G6F668
Created by admin on Fri Dec 15 16:37:27 GMT 2023 , Edited by admin on Fri Dec 15 16:37:27 GMT 2023
PRIMARY
PUBCHEM
6917768
Created by admin on Fri Dec 15 16:37:27 GMT 2023 , Edited by admin on Fri Dec 15 16:37:27 GMT 2023
PRIMARY
EPA CompTox
DTXSID101024280
Created by admin on Fri Dec 15 16:37:27 GMT 2023 , Edited by admin on Fri Dec 15 16:37:27 GMT 2023
PRIMARY
ChEMBL
CHEMBL2107438
Created by admin on Fri Dec 15 16:37:27 GMT 2023 , Edited by admin on Fri Dec 15 16:37:27 GMT 2023
PRIMARY
NCI_THESAURUS
C90925
Created by admin on Fri Dec 15 16:37:27 GMT 2023 , Edited by admin on Fri Dec 15 16:37:27 GMT 2023
PRIMARY