DELPHINIDIN CHLORIDE

[Cl-].OC1=CC(O)=C2C=C(O)C(=[O+]C2=C1)C3=CC(O)=C(O)C(O)=C3

InChIKey=FFNDMZIBVDSQFI-UHFFFAOYSA-N

InChI=1S/C15H10O7.ClH/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6;/h1-5H,(H5-,16,17,18,19,20,21);1H

Targets

Primary Target	Pharmacology	Potency
regulation of membrane permeability 2 Target ID: GO:0090559 Sources: https://adisinsight.springer.com/drugs/800003473	Inhibitor 8297
Vascular endothelial growth factor receptor 2 104 Target ID: CHEMBL279 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27484508	Inhibitor 8297	5.09 nM [IC50]
Epidermal growth factor receptor erbB1 58 Target ID: CHEMBL203 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27484508	Inhibitor 8297	6.27 nM [IC50]

PubMed

Title	Date	PubMed
Anthocyanins induce cell cycle perturbations and apoptosis in different human cell lines.	2004 Aug	15016660
Induction of apoptosis by the Anthocyanidins through regulation of Bcl-2 gene and activation of c-Jun N-terminal kinase cascade in hepatoma cells.	2005 Mar 9	15740068
Anthocyanins protect against A2E photooxidation and membrane permeabilization in retinal pigment epithelial cells.	2005 May-Jun	15745429
Delphinidin and cyanidin inhibit PDGF(AB)-induced VEGF release in vascular smooth muscle cells by preventing activation of p38 MAPK and JNK.	2006 Oct	16921400
Dietary flavones and flavonoles are inhibitors of poly(ADP-ribose)polymerase-1 in pulmonary epithelial cells.	2007 Oct	17884996
PGK1 induction by a hydrogen peroxide treatment is suppressed by antioxidants in human colon carcinoma cells.	2008 Jul	18603805
Delphinidin attenuates stress injury induced by oxidized low-density lipoprotein in human umbilical vein endothelial cells.	2010 Jan 5	19818742
Antifibrotic activity of anthocyanidin delphinidin in carbon tetrachloride-induced hepatotoxicity in mice.	2010 Jun 4	20371262
Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174T.	2013 Apr 26	23419638

Patents

Name

Type

Language

DELPHINIDIN CHLORIDE

Common Name

English

DELPHINIDIN [MI]

Common Name

English

3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-1-BENZOPYRYLIUM CHLORIDE (1:1)

Systematic Name

English

DELPHINIDIN

Common Name

English

DELPHINIDOL

Common Name

English

3,3',4',5,5',7-HEXAHYDROXYFLAVYLIUM CHLORIDE

Systematic Name

English

3,3',4',5,5',7-HEXAHYDROXY-2-PHENYLBENZOPYRYLIUM CHLORIDE

Common Name

English

Classification Tree Code System Code

DSLD