Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C15H11O7 |
| Molecular Weight | 303.2436 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 1 |
SHOW SMILES / InChI
SMILES
OC1=CC2=[O+]C(C3=CC(O)=C(O)C(O)=C3)=C(O)C=C2C(O)=C1
InChI
InChIKey=JKHRCGUTYDNCLE-UHFFFAOYSA-O
InChI=1S/C15H10O7/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6/h1-5H,(H5-,16,17,18,19,20,21)/p+1
| Molecular Formula | C15H10O7 |
| Molecular Weight | 302.2357 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: GO:0090559 Sources: https://adisinsight.springer.com/drugs/800003473 |
|||
Target ID: CHEMBL279 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27484508 |
5.09 nM [IC50] | ||
Target ID: CHEMBL203 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27484508 |
6.27 nM [IC50] |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174T. | 2013-04-26 |
|
| Antifibrotic activity of anthocyanidin delphinidin in carbon tetrachloride-induced hepatotoxicity in mice. | 2010-06-04 |
|
| Delphinidin attenuates stress injury induced by oxidized low-density lipoprotein in human umbilical vein endothelial cells. | 2010-01-05 |
|
| Fyn kinase is a direct molecular target of delphinidin for the inhibition of cyclooxygenase-2 expression induced by tumor necrosis factor-alpha. | 2009-04-01 |
|
| Delphinidin modulates the DNA-damaging properties of topoisomerase II poisons. | 2009-03-16 |
|
| PGK1 induction by a hydrogen peroxide treatment is suppressed by antioxidants in human colon carcinoma cells. | 2008-07 |
|
| Dietary flavones and flavonoles are inhibitors of poly(ADP-ribose)polymerase-1 in pulmonary epithelial cells. | 2007-10 |
|
| Delphinidin and cyanidin inhibit PDGF(AB)-induced VEGF release in vascular smooth muscle cells by preventing activation of p38 MAPK and JNK. | 2006-10 |
|
| Induction of apoptosis by the Anthocyanidins through regulation of Bcl-2 gene and activation of c-Jun N-terminal kinase cascade in hepatoma cells. | 2005-03-09 |
|
| Anthocyanins protect against A2E photooxidation and membrane permeabilization in retinal pigment epithelial cells. | 2005-03-05 |
|
| Anthocyanins induce cell cycle perturbations and apoptosis in different human cell lines. | 2004-08 |
|
| The metabolism of dietary polyphenols and the relevance to circulating levels of conjugated metabolites. | 2002-11 |
|
| Antioxidant activity of black currant anthocyanin aglycons and their glycosides measured by chemiluminescence in a neutral pH region and in human plasma. | 2002-08-28 |
|
| Orally administered delphinidin 3-rutinoside and cyanidin 3-rutinoside are directly absorbed in rats and humans and appear in the blood as the intact forms. | 2001-03 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:48:51 GMT 2025
by
admin
on
Mon Mar 31 22:48:51 GMT 2025
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| Record UNII |
031A4BN94T
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| Record Status |
Validated (UNII)
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| Record Version |
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128853
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13270-61-6
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031A4BN94T
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admin on Mon Mar 31 22:48:51 GMT 2025 , Edited by admin on Mon Mar 31 22:48:51 GMT 2025
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| Related Record | Type | Details | ||
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SALT/SOLVATE -> PARENT |