Emavusertib Phosphate

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C24H25N7O5.H3O4P
Molecular Weight	589.4944
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OP(O)(O)=O.CC1=CC(=CC=N1)C2=NC(=CO2)C(=O)NC3=CC4=C(N=C(O4)N5CCOCC5)N=C3N6CC[C@@H](O)C6

InChI

InChIKey=VJPANLKVEFNCDL-PKLMIRHRSA-N

InChI=1S/C24H25N7O5.H3O4P/c1-14-10-15(2-4-25-14)23-27-18(13-35-23)22(33)26-17-11-19-20(28-21(17)31-5-3-16(32)12-31)29-24(36-19)30-6-8-34-9-7-30;1-5(2,3)4/h2,4,10-11,13,16,32H,3,5-9,12H2,1H3,(H,26,33);(H3,1,2,3,4)/t16-;/m1./s1

HIDE SMILES / InChI

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Interleukin-1 receptor-associated kinase 4 9 Target ID: CHEMBL3778 Sources: https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20150716&CC=WO&NR=2015104688A1&KC=A1	Inhibitor 8504

Name

Type

Language

CA-4948-phosphate

Preferred Name

English

Emavusertib Phosphate

Official Name

English

EMAVUSERTIB PHOSPHATE [USAN]

Common Name

English

N-{5-[(3R)-3-hydroxypyrrolidin-1-yl]-2-(morpholin-4-yl)[1,3]oxazolo[4,5-b]pyridin-6-yl}-2-(2-methylpyridin-4-yl)-1,3-oxazole-4-carboxamide phosphate

Systematic Name

English

4-Oxazolecarboxamide, N-[5-[(3R)-3-hydroxy-1-pyrrolidinyl]-2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl]-2-(2-methyl-4-pyridinyl)-, phosphate (1:1)

Systematic Name

English

Code System Code Type Description

NCI_THESAURUS

C199039