Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C19H18F2N4O3.ClH |
| Molecular Weight | 424.829 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CN1C(=O)C(OC2=C(F)C=C(F)C=C2)=CC3=CN=C(NC4CCOCC4)N=C13
InChI
InChIKey=RQHSAIGGUWVOBG-UHFFFAOYSA-N
InChI=1S/C19H18F2N4O3.ClH/c1-25-17-11(10-22-19(24-17)23-13-4-6-27-7-5-13)8-16(18(25)26)28-15-3-2-12(20)9-14(15)21;/h2-3,8-10,13H,4-7H2,1H3,(H,22,23,24);1H
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: Q16539|||Q8TDX0 Gene ID: 1432.0 Gene Symbol: MAPK14 Target Organism: Homo sapiens (Human) |
0.2 nM [Kd] | ||
Target ID: P45984|||Q15711 Gene ID: 5601.0 Gene Symbol: MAPK9 Target Organism: Homo sapiens (Human) |
9.0 nM [Kd] | ||
Target ID: P53779 Gene ID: 5602.0 Gene Symbol: MAPK10 Target Organism: Homo sapiens (Human) |
3.0 nM [Kd] | ||
Target ID: Q9UBE8 Gene ID: 51701.0 Gene Symbol: NLK Target Organism: Homo sapiens (Human) |
6.0 nM [Kd] |
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MANUFACTURER PRODUCT INFORMATION |
6-(2,4-DIFLUOROPHENOXY)-8-METHYL-2-(TETRAHYDROPYRAN-4-YLAMINO)PYRIDO(2,3-D)PYRIMIDIN-7-ONE HYDROCHLORIDE
Created by
admin on Sat Dec 16 11:03:57 GMT 2023 , Edited by admin on Sat Dec 16 11:03:57 GMT 2023
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DTXSID60712354
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E89N7YW9YQ
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54580957
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admin on Sat Dec 16 11:03:57 GMT 2023 , Edited by admin on Sat Dec 16 11:03:57 GMT 2023
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449808-64-4
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admin on Sat Dec 16 11:03:57 GMT 2023 , Edited by admin on Sat Dec 16 11:03:57 GMT 2023
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ACTIVE MOIETY
SUBSTANCE RECORD
