U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C8H9AsNO5.Bi.O
Molecular Weight 499.0622
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GLYCOBIARSOL

SMILES

[O--].[Bi+3].OCC(=O)NC1=CC=C(C=C1)[As](O)([O-])=O

InChI

InChIKey=UPCVPFKBUJAADX-UHFFFAOYSA-M
InChI=1S/C8H10AsNO5.Bi.O/c11-5-8(12)10-7-3-1-6(2-4-7)9(13,14)15;;/h1-4,11H,5H2,(H,10,12)(H2,13,14,15);;/q;+3;-2/p-1

HIDE SMILES / InChI

Description

Glycobiarsol was known under the brand name Milibis. Glycobiarsol is found to be very effective in intestinal infections. Milibis is an antiprotozoal agent that has been used in humans as well as in dogs.

Originator

Sanofi-Aventis
64

Approval Year

1949
70

Conditions

ConditionModalityTargetsHighest PhaseProduct
Amebiasis
11
 Curative
Approved
8,429
Milibis

PubMed

Patents

US20060078604
1
US8591941
6

Sample Use Guides

In Vivo Use Guide
220 mg of the drug per kilogram body weight
Route of Administration: Oral
In Vitro Use Guide
GLYCOBIARSOL was reported to be effective in vitro at about 30 ug/ml in egg-infusion medium
PARENT (SALT/SOLVATE)
Structure of GLYCARSAMIDE
SUBSTANCE RECORD
Structure of GLYCOBIARSOL
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966