GLYCOBIARSOL

US Previously Marketed

First approved in 1949

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H9AsNO5.Bi.O
Molecular Weight	499.0622
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[O--].[Bi+3].OCC(=O)NC1=CC=C(C=C1)[As](O)([O-])=O

InChI

InChIKey=UPCVPFKBUJAADX-UHFFFAOYSA-M

InChI=1S/C8H10AsNO5.Bi.O/c11-5-8(12)10-7-3-1-6(2-4-7)9(13,14)15;;/h1-4,11H,5H2,(H,10,12)(H2,13,14,15);;/q;+3;-2/p-1

HIDE SMILES / InChI

Molecular Formula	C8H8AsNO5
Molecular Weight	273.0744
Charge	-2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Bi
Molecular Weight	208.9804
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	HO
Molecular Weight	17.0073
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13214428 | https://www.drugs.com/international/glycobiarsol.html | https://www.fda.gov/ohrms/dockets/98fr/FR1972_07_08_13496(8451).pdf | http://drugs-about.com/drugs-m/milibis.html

Glycobiarsol was known under the brand name Milibis. Glycobiarsol is found to be very effective in intestinal infections. Milibis is an antiprotozoal agent that has been used in humans as well as in dogs.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Amebiasis 11 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14023142 https://www.ncbi.nlm.nih.gov/pubmed/14872716	Curative		Approved 8583	Milibis Approved Use Antiprotozoal agent, amebicide

PubMed

Title	Date	PubMed
Glycobiarsol for the control of Trichuris vulpis infection in the dog.	1969-08	5389346
[Treatment of trichocephaliasis with glycobiarsol].	1962-01	13900050
The trichomonacidal activity of milibis (glycobiarsol).	1954-11	13214428

Patents

Sample Use Guides

In Vivo Use Guide

220 mg of the drug per kilogram body weight

Route of Administration: Oral

In Vitro Use Guide

GLYCOBIARSOL was reported to be effective in vitro at about 30 ug/ml in egg-infusion medium

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:51:33 GMT 2025` Edited by `admin` on `Mon Mar 31 17:51:33 GMT 2025`
Record UNII	E3U8347QWJ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MILIBIS

Preferred Name

English

GLYCOBIARSOL

Official Name

English

GLYCOBIARSOL [MI]

Common Name

English

glycobiarsol [INN]

Common Name

English

GLYCOBIARSOL [MART.]

Common Name

English

(Hydrogen N-glycoloylarsanilato)oxobismuth

Common Name

English

BISMUTH, ((4-((HYDROXYACETYL)AMINO)PHENYL)ARSONATO(1-))OXO-

Common Name

English

BISMUTH GLYCOLLYLARSANILATE

Common Name

English

GLYCOBIARSOL [GREEN BOOK]

Common Name

English

Glycobiarsol [WHO-DD]

Common Name

English

NSC-221709

Code

English

Classification Tree Code System Code

WHO-ATC

P01AR03