U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C9H13N2O9P
Molecular Weight 324.1813
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of URIDINE MONOPHOSPHATE

SMILES

O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(O)=O)N2C=CC(=O)NC2=O

InChI

InChIKey=DJJCXFVJDGTHFX-XVFCMESISA-N
InChI=1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
PubMed

PubMed

TitleDatePubMed
Inhibition of herpes simplex virus DNA polymerase by purine ribonucleoside monophosphates.
1986 Feb 5
Antibody-nucleic acid complexes. Oligo(dG)n and -(dT)n specificities associated with anti-DNA antibodies from autoimmune MRL mice.
1989 Dec 26
Comparison between tryptophan methoxyindole and kynurenine metabolic pathways in normal and preterm neonates and in neonates with acute fetal distress.
1998 Jul
Methylenetetrahydrofolate reductase polymorphism and susceptibility to breast cancer.
2002
RNA editing: complexity and complications.
2002 Aug
Translational regulation of prostaglandin endoperoxide H synthase-1 mRNA in megakaryocytic MEG-01 cells. Specific protein binding to a conserved 20-nucleotide CIS element in the 3'-untranslated region.
2002 Nov 22
Microarray analysis of orthologous genes: conservation of the translational machinery across species at the sequence and expression level.
2003
Plasma pyridoxal 5'-phosphate concentration is correlated with functional vitamin B-6 indices in patients with rheumatoid arthritis and marginal vitamin B-6 status.
2003 Apr
The poliovirus 2C cis-acting replication element-mediated uridylylation of VPg is not required for synthesis of negative-sense genomes.
2003 Sep
cis-acting elements at opposite ends of the Citrus tristeza virus genome differ in initiation and termination of subgenomic RNAs.
2004 Apr 25
Complete cycles of bloodstream trypanosome RNA editing in vitro.
2004 Jun
Reconstruction of ancestral protein sequences and its applications.
2004 Sep 17
Protein-protein interactions of the hyperthermophilic archaeon Pyrococcus horikoshii OT3.
2005
Two cis-acting elements in negative RNA strand of Hepatitis C virus involved in synthesis of positive RNA strand in vitro.
2005
A comprehensive update of the sequence and structure classification of kinases.
2005 Mar 16
Mutational analysis of the SARS virus Nsp15 endoribonuclease: identification of residues affecting hexamer formation.
2005 Nov 11
Design, synthesis and structural analysis of novel bent DNAs containing cyclic uridylate dimer analogues.
2006
RNA recognition and cleavage by the SARS coronavirus endoribonuclease.
2006 Aug 11
A multispecies comparison of the metazoan 3'-processing downstream elements and the CstF-64 RNA recognition motif.
2006 Mar 16
KREPA4, an RNA binding protein essential for editosome integrity and survival of Trypanosoma brucei.
2006 May
Molecular dynamics DFT:B3LYP study of guanosinetriphosphate conversion into guanosinemonophosphate upon Mg2+ chelation of alpha and beta phosphate oxygens of the triphosphate tail.
2006 May 14
RNA-protein interactions in assembled editing complexes in trypanosomes.
2007
The role of Ureaplasma nucleoside monophosphate kinases in the synthesis of nucleoside triphosphates.
2007 Apr
Modulation of mRNA stability as a novel therapeutic approach.
2007 Apr
The RNA-binding protein HuD binds acetylcholinesterase mRNA in neurons and regulates its expression after axotomy.
2007 Jan 17
Identification of quorum sensing-related regulons in Vibrio vulnificus by two-dimensional gel electrophoresis and differentially displayed reverse transcriptase PCR.
2007 Jun
RNA-editing-associated protein 1 null mutant reveals link to mitochondrial RNA stability.
2007 Jun
Expression of RNA virus proteins by RNA polymerase II dependent expression plasmids is hindered at multiple steps.
2007 Jun 5
Structural and enzymatic investigation of the Sulfolobus solfataricus uridylate kinase shows competitive UTP inhibition and the lack of GTP stimulation.
2007 Mar 13
Turkey coronavirus non-structure protein NSP15--an endoribonuclease.
2008
Identification of a bacterial-like HslVU protease in the mitochondria of Trypanosoma brucei and its role in mitochondrial DNA replication.
2008 Apr 18
Comparative phylogenomics and multi-gene cluster analyses of the Citrus Huanglongbing (HLB)-associated bacterium Candidatus Liberibacter.
2008 Aug 28
Reversible sialylation: synthesis of cytidine 5'-monophospho-N-acetylneuraminic acid from cytidine 5'-monophosphate with alpha2,3-sialyl O-glycan-, glycolipid-, and macromolecule-based donors yields diverse sialylated products.
2008 Jan 8
Structural analysis reveals conformational plasticity in the recognition of RNA 3' ends by the human La protein.
2008 Jun
Trypanosoma brucei RNA editing protein TbMP42 (band VI) is crucial for the endonucleolytic cleavages but not the subsequent steps of U-deletion and U-insertion.
2008 Jun
Complete sequence and analysis of the mitochondrial genome of Hemiselmis andersenii CCMP644 (Cryptophyceae).
2008 May 12
The binary protein interactome of Treponema pallidum--the syphilis spirochete.
2008 May 28
The crystal structure of UMP kinase from Bacillus anthracis (BA1797) reveals an allosteric nucleotide-binding site.
2008 Sep 19
Dietary intake of selected B vitamins in relation to risk of major cancers in women.
2008 Sep 2
Improving the quality of infant sleep through the inclusion at supper of cereals enriched with tryptophan, adenosine-5'-phosphate, and uridine-5'-phosphate.
2009 Dec
Unique GTP-binding pocket and allostery of uridylate kinase from a gram-negative phytopathogenic bacterium.
2009 Jan 30
Post-transcriptional regulation of gene expression in plants during abiotic stress.
2009 Jul 10
Expression and subcellular localization of kinetoplast-associated proteins in the different developmental stages of Trypanosoma cruzi.
2009 Jun 4
TbPIF5 is a Trypanosoma brucei mitochondrial DNA helicase involved in processing of minicircle Okazaki fragments.
2009 Sep
The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin ligase.
2009 Sep 10
The Alveolate Perkinsus marinus: biological insights from EST gene discovery.
2010 Apr 7
Novel naphthalene-based inhibitors of Trypanosoma brucei RNA editing ligase 1.
2010 Aug 24
Flavin-dependent thymidylate synthase: a novel pathway towards thymine.
2010 Jan 1
RNA virus replication complexes.
2010 Jul 22
Identifying essential genes in bacterial metabolic networks with machine learning methods.
2010 May 3
Patents
Name Type Language
URIDINE MONOPHOSPHATE
Systematic Name English
URIDINE PHOSPHATE [WHO-DD]
Common Name English
URIDINE PHOSPHATE
WHO-DD  
Systematic Name English
URIDINE 5'-PHOSPHORIC ACID
Common Name English
URIDINE 5'-MONOPHOSPHATE
Systematic Name English
UMP
Common Name English
5'-URIDYLIC ACID
MI  
Systematic Name English
5'-URIDYLIC ACID [MI]
Common Name English
Code System Code Type Description
ECHA (EC/EINECS)
200-408-0
Created by admin on Tue Oct 22 19:50:32 UTC 2019 , Edited by admin on Tue Oct 22 19:50:32 UTC 2019
PRIMARY
CAS
58-97-9
Created by admin on Tue Oct 22 19:50:32 UTC 2019 , Edited by admin on Tue Oct 22 19:50:32 UTC 2019
PRIMARY
PUBCHEM
6030
Created by admin on Tue Oct 22 19:50:32 UTC 2019 , Edited by admin on Tue Oct 22 19:50:32 UTC 2019
PRIMARY
EVMPD
SUB126222
Created by admin on Tue Oct 22 19:50:32 UTC 2019 , Edited by admin on Tue Oct 22 19:50:32 UTC 2019
PRIMARY
WIKIPEDIA
URIDINE MONOPHOSPHATE
Created by admin on Tue Oct 22 19:50:32 UTC 2019 , Edited by admin on Tue Oct 22 19:50:32 UTC 2019
PRIMARY
MERCK INDEX
M11336
Created by admin on Tue Oct 22 19:50:32 UTC 2019 , Edited by admin on Tue Oct 22 19:50:32 UTC 2019
PRIMARY Merck Index