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Details

Stereochemistry UNKNOWN
Molecular Formula C12H14N2O3.C10H16O4S
Molecular Weight 466.548
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIPROQUALONE CAMSILATE, (+)-

SMILES

CC1(C)[C@@H]2CC[C@@]1(CS(O)(=O)=O)C(=O)C2.CC3=NC4=C(C=CC=C4)C(=O)N3CC(O)CO

InChI

InChIKey=AJNMCFBQWSXQHS-STOWLHSFSA-N
InChI=1S/C12H14N2O3.C10H16O4S/c1-8-13-11-5-3-2-4-10(11)12(17)14(8)6-9(16)7-15;1-9(2)7-3-4-10(9,8(11)5-7)6-15(12,13)14/h2-5,9,15-16H,6-7H2,1H3;7H,3-6H2,1-2H3,(H,12,13,14)/t;7-,10-/m.1/s1

HIDE SMILES / InChI
Diproqualone was used primarily for the treatment of inflammatory pain associated with osteoarthritis. The analgesic activity of diproqualoneis synergistic with that of noramidopyrine. It also display anti-inflammatory action in the rat, inhibiting plantar edema with dextran or serotonin, atopic edema from ovalbumin, etc. It has spasmolytic, anticholinergic and antihistaminic action in higher doses. It is not hypnotic and has no anticonvulsant effects. The therapeutic symptoms for diproqualone are all types of pain: postoperative, posttraumatic, dental, neuritis, anti-inflammatory arthritis, etc.

Approval Year

PubMed

PubMed

TitleDatePubMed
Synthesis of new 2,3-dihydroquinazolin-4(1H)-one derivatives for analgesic and anti-inflammatory evaluation.
2010-05
Name Type Language
DIPROQUALONE CAMSILATE, (+)-
Common Name English
BICYCLO(2.2.1)HEPTANE-2-SULFONIC ACID, 4,7,7-TRIMETHYL-3-OXO-, (1S-ENDO)-, COMPD. WITH (+)-3-(2,3-DIHYDROXYPROPYL)-2-METHYL-4(3H)-QUINAZOLINONE (1:1)
Preferred Name English
Code System Code Type Description
FDA UNII
DZ5M7UH6PG
Created by admin on Mon Mar 31 21:15:06 GMT 2025 , Edited by admin on Mon Mar 31 21:15:06 GMT 2025
PRIMARY
CAS
13572-62-8
Created by admin on Mon Mar 31 21:15:06 GMT 2025 , Edited by admin on Mon Mar 31 21:15:06 GMT 2025
PRIMARY
EPA CompTox
DTXSID60929127
Created by admin on Mon Mar 31 21:15:06 GMT 2025 , Edited by admin on Mon Mar 31 21:15:06 GMT 2025
PRIMARY