DIPROQUALONE CAMSILATE, (+)-

Details

Stereochemistry	UNKNOWN
Molecular Formula	C12H14N2O3.C10H16O4S
Molecular Weight	466.548
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DIPROQUALONE CAMSILATE, (+)-

Structure Search

SMILES

CC1(C)[C@@H]2CC[C@@]1(CS(O)(=O)=O)C(=O)C2.CC3=NC4=C(C=CC=C4)C(=O)N3CC(O)CO

InChI

InChIKey=AJNMCFBQWSXQHS-STOWLHSFSA-N

InChI=1S/C12H14N2O3.C10H16O4S/c1-8-13-11-5-3-2-4-10(11)12(17)14(8)6-9(16)7-15;1-9(2)7-3-4-10(9,8(11)5-7)6-15(12,13)14/h2-5,9,15-16H,6-7H2,1H3;7H,3-6H2,1-2H3,(H,12,13,14)/t;7-,10-/m.1/s1

HIDE SMILES / InChI

Molecular Formula	C12H14N2O3
Molecular Weight	234.2512
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	C10H16O4S
Molecular Weight	232.297
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/20232372 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 457, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | (2013) Progress in Drug Research, page 272, retrieved from: https://books.google.ru/books?id=wFX2BwAAQBAJ

Diproqualone was used primarily for the treatment of inflammatory pain associated with osteoarthritis. The analgesic activity of diproqualoneis synergistic with that of noramidopyrine. It also display anti-inflammatory action in the rat, inhibiting plantar edema with dextran or serotonin, atopic edema from ovalbumin, etc. It has spasmolytic, anticholinergic and antihistaminic action in higher doses. It is not hypnotic and has no anticonvulsant effects. The therapeutic symptoms for diproqualone are all types of pain: postoperative, posttraumatic, dental, neuritis, anti-inflammatory arthritis, etc.

Approval Year

PubMed

Title	Date	PubMed
Synthesis of new 2,3-dihydroquinazolin-4(1H)-one derivatives for analgesic and anti-inflammatory evaluation.	2010-05	20232372

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:15:06 GMT 2025` Edited by `admin` on `Mon Mar 31 21:15:06 GMT 2025`
Record UNII	DZ5M7UH6PG
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIPROQUALONE CAMSILATE, (+)-

Common Name

English

BICYCLO(2.2.1)HEPTANE-2-SULFONIC ACID, 4,7,7-TRIMETHYL-3-OXO-, (1S-ENDO)-, COMPD. WITH (+)-3-(2,3-DIHYDROXYPROPYL)-2-METHYL-4(3H)-QUINAZOLINONE (1:1)

Preferred Name

English

Code System Code Type Description

FDA UNII

DZ5M7UH6PG

Created by admin on Mon Mar 31 21:15:06 GMT 2025 , Edited by admin on Mon Mar 31 21:15:06 GMT 2025

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CAS

13572-62-8

Created by admin on Mon Mar 31 21:15:06 GMT 2025 , Edited by admin on Mon Mar 31 21:15:06 GMT 2025

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EPA CompTox

DTXSID60929127

Created by admin on Mon Mar 31 21:15:06 GMT 2025 , Edited by admin on Mon Mar 31 21:15:06 GMT 2025

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