Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C13H17N2O4S2.K |
| Molecular Weight | 368.513 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)CSCC=C)C([O-])=O
InChI
InChIKey=ONYTXCTVWDZLFD-GITWGATASA-M
InChI=1S/C13H18N2O4S2.K/c1-4-5-20-6-7(16)14-8-10(17)15-9(12(18)19)13(2,3)21-11(8)15;/h4,8-9,11H,1,5-6H2,2-3H3,(H,14,16)(H,18,19);/q;+1/p-1/t8-,9+,11-;/m1./s1
Approval Year
Doses
| Dose | Population | Adverse events |
|---|---|---|
1000000 unit 1 times / day multiple, intramuscular Highest studied dose Dose: 1000000 unit, 1 times / day Route: intramuscular Route: multiple Dose: 1000000 unit, 1 times / day Sources: |
unhealthy, 23 years n = 1 Health Status: unhealthy Condition: rheumatoid spondylitis Age Group: 23 years Sex: M Population Size: 1 Sources: |
Other AEs: Nausea, Increased salivation... |
600000 unit single, intramuscular Dose: 600000 unit Route: intramuscular Route: single Dose: 600000 unit Sources: |
unhealthy, 23 years n = 1 Health Status: unhealthy Condition: rheumatoid spondylitis Age Group: 23 years Sex: M Population Size: 1 Sources: |
Disc. AE: Anaphylactic shock... AEs leading to discontinuation/dose reduction: Anaphylactic shock (severe) Sources: |
AEs
| AE | Significance | Dose | Population |
|---|---|---|---|
| Increased salivation | 1000000 unit 1 times / day multiple, intramuscular Highest studied dose Dose: 1000000 unit, 1 times / day Route: intramuscular Route: multiple Dose: 1000000 unit, 1 times / day Sources: |
unhealthy, 23 years n = 1 Health Status: unhealthy Condition: rheumatoid spondylitis Age Group: 23 years Sex: M Population Size: 1 Sources: |
|
| Nausea | mild | 1000000 unit 1 times / day multiple, intramuscular Highest studied dose Dose: 1000000 unit, 1 times / day Route: intramuscular Route: multiple Dose: 1000000 unit, 1 times / day Sources: |
unhealthy, 23 years n = 1 Health Status: unhealthy Condition: rheumatoid spondylitis Age Group: 23 years Sex: M Population Size: 1 Sources: |
| Anaphylactic shock | severe Disc. AE |
600000 unit single, intramuscular Dose: 600000 unit Route: intramuscular Route: single Dose: 600000 unit Sources: |
unhealthy, 23 years n = 1 Health Status: unhealthy Condition: rheumatoid spondylitis Age Group: 23 years Sex: M Population Size: 1 Sources: |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Use of penicillin O in patients hypersensitive to pencilling G. | 1950 Jul 1 |
|
| Clinical and pharmacologic studies with allylmercaptomethyl penicillin (penicillin O). | 1951 Aug |
|
| Studies on the mechanism of the formation of the penicillin antigen. I. Delayed allergic cross-reactions among penicillin G and its degradation products. | 1960 Dec 1 |
|
| Some immunochemical properties of penicillenic acid. An antigenic determinant derived from penicillin. | 1960 Dec 1 |
Patents
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
897-61-0
Created by
admin on Sat Dec 16 09:53:15 GMT 2023 , Edited by admin on Sat Dec 16 09:53:15 GMT 2023
|
PRIMARY | |||
|
m8478
Created by
admin on Sat Dec 16 09:53:15 GMT 2023 , Edited by admin on Sat Dec 16 09:53:15 GMT 2023
|
PRIMARY | Merck Index | ||
|
23675011
Created by
admin on Sat Dec 16 09:53:15 GMT 2023 , Edited by admin on Sat Dec 16 09:53:15 GMT 2023
|
PRIMARY | |||
|
CHEMBL2105909
Created by
admin on Sat Dec 16 09:53:15 GMT 2023 , Edited by admin on Sat Dec 16 09:53:15 GMT 2023
|
PRIMARY | |||
|
DP2X0D6YBT
Created by
admin on Sat Dec 16 09:53:15 GMT 2023 , Edited by admin on Sat Dec 16 09:53:15 GMT 2023
|
PRIMARY | |||
|
DTXSID70237861
Created by
admin on Sat Dec 16 09:53:15 GMT 2023 , Edited by admin on Sat Dec 16 09:53:15 GMT 2023
|
PRIMARY |
ACTIVE MOIETY
SUBSTANCE RECORD
