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Details

Stereochemistry ACHIRAL
Molecular Formula C14H8Cl4
Molecular Weight 318.025
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of O,P'-DDE

SMILES

ClC(Cl)=C(C1=CC=C(Cl)C=C1)C2=C(Cl)C=CC=C2

InChI

InChIKey=ZDYJWDIWLRZXDB-UHFFFAOYSA-N
InChI=1S/C14H8Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8H

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Influence of chlorinated hydrocarbons, Hg2+ and methyl-Hg+ on steroid hormone receptors from eggshell gland mucosa of domestic fowls and ducks.
1991
Interaction of environmental chemicals with the estrogen and progesterone receptors from the oviduct of the American alligator.
1996 Dec
Xenobiotic interaction with and alteration of channel catfish estrogen receptor.
1997 Dec
Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells.
1998 Jul
Differential estrogen receptor binding of estrogenic substances: a species comparison.
2000 Nov 15
Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens.
2001 Mar
Screening of environmental contaminants for ecdysteroid agonist and antagonist activity using the Drosophila melanogaster B(II) cell in vitro assay.
2001 Sep
Development of a fish reporter gene system for the assessment of estrogenic compounds and sewage treatment plant effluents.
2002 Sep
In ovo exposure to o,p -DDE affects sexual development but not sexual differentiation in Japanese medaka (Oryzias latipes).
2003 Jan
Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.
2003 Oct
Recombinant human estrogen, androgen and progesterone receptors for detection of potential endocrine disruptors.
2004 Feb
Organochlorine micropollutants in the Jiulong River Estuary and Western Xiamen Sea, China.
2005
CAR and PXR: xenosensors of endocrine disrupters?
2005 Aug 15
Distribution and mass inventory of total dichlorodiphenyldichloroethylene in the water column of the southern California bight.
2005 Nov 1
Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: a potential novel mechanism of endocrine disruption.
2006 Dec
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.
2006 Nov
DDT- and DDE-induced disruption of ovarian steroidogenesis in prepubertal porcine ovarian follicles: a possible interaction with the main steroidogenic enzymes and estrogen receptor beta.
2007 Dec
Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism.
2008 Apr
Screening of some anti-progestin endocrine disruptors using a recombinant yeast based in vitro bioassay.
2008 Apr
A novel pretreatment approach for fast determination of organochlorine pesticides in biotic samples.
2008 May
Cytotoxicity and decreased corticosterone production in adrenocortical Y-1 cells by 3-methylsulfonyl-DDE and structurally related molecules.
2009 Apr
Differential effects exerted on human mammary epithelial cells by environmentally relevant organochlorine pesticides either individually or in combination.
2009 Aug 14
Effects of o,p'-DDE, heptachlor, and 17beta-estradiol on vitellogenin gene expression and the growth hormone/insulin-like growth factor-I axis in the tilapia, Oreochromis mossambicus.
2009 May
The influence of polychlorinated biphenyls (PCBs), dichlorodiphenyltrichloroethane (DDT) and its metabolite-dichlorodiphenyldichloroethylene (DDE) on mRNA expression for NP-I/OT and PGA, involved in oxytocin synthesis in bovine granulosa and luteal cells.
2009 Nov
Comparison of relative binding affinities to fish and mammalian estrogen receptors: the regulatory implications.
2010 Feb 15
Differential effect of DDT, DDE, and DDD on COX-2 expression in the human trophoblast derived HTR-8/SVneo cells.
2012 Nov
The organochlorine o,p'-DDT plays a role in coactivator-mediated MAPK crosstalk in MCF-7 breast cancer cells.
2012 Sep
Name Type Language
O,P'-DDE
Common Name English
O,P'-DICHLORODIPHENYLDICHLOROETHYLENE
Common Name English
2,4'-DICHLORODIPHENYLDICHLOROETHYLENE
Common Name English
NSC-59908
Code English
2-(2-CHLOROPHENYL)-2-(4-CHLOROPHENYL)-1,1-DICHLOROETHYLENE
Systematic Name English
DDE, O,P'-
Common Name English
ETHYLENE, 1,1-DICHLORO-2-(O-CHLOROPHENYL)-2-(P-CHLOROPHENYL)-
Common Name English
2,4'-DDE
Common Name English
BENZENE, 1-CHLORO-2-(2,2-DICHLORO-1-(4-CHLOROPHENYL)ETHENYL)-
Systematic Name English
2,2-(2-CHLOROPHENYL-4'-CHLOROPHENYL)-1,1-DICHLOROETHENE
Systematic Name English
1-CHLORO-2-(2,2-DICHLORO-1-(4-CHLOROPHENYL)ETHENYL)BENZENE
Systematic Name English
1-CHLORO-2-(2,2-DICHLORO-1-(4-CHLOROPHENYL)VINYL)BENZENE
Systematic Name English
Code System Code Type Description
CAS
3424-82-6
Created by admin on Fri Dec 15 14:58:03 GMT 2023 , Edited by admin on Fri Dec 15 14:58:03 GMT 2023
PRIMARY
FDA UNII
DM084YLQ1L
Created by admin on Fri Dec 15 14:58:03 GMT 2023 , Edited by admin on Fri Dec 15 14:58:03 GMT 2023
PRIMARY
EPA CompTox
DTXSID4022313
Created by admin on Fri Dec 15 14:58:03 GMT 2023 , Edited by admin on Fri Dec 15 14:58:03 GMT 2023
PRIMARY
ECHA (EC/EINECS)
222-318-0
Created by admin on Fri Dec 15 14:58:03 GMT 2023 , Edited by admin on Fri Dec 15 14:58:03 GMT 2023
PRIMARY
NSC
59908
Created by admin on Fri Dec 15 14:58:03 GMT 2023 , Edited by admin on Fri Dec 15 14:58:03 GMT 2023
PRIMARY
PUBCHEM
246598
Created by admin on Fri Dec 15 14:58:03 GMT 2023 , Edited by admin on Fri Dec 15 14:58:03 GMT 2023
PRIMARY