Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C14H8Cl4 |
| Molecular Weight | 318.025 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC(Cl)=C(C1=CC=C(Cl)C=C1)C2=C(Cl)C=CC=C2
InChI
InChIKey=ZDYJWDIWLRZXDB-UHFFFAOYSA-N
InChI=1S/C14H8Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8H
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Influence of chlorinated hydrocarbons, Hg2+ and methyl-Hg+ on steroid hormone receptors from eggshell gland mucosa of domestic fowls and ducks. | 1991 |
|
| Interaction of environmental chemicals with the estrogen and progesterone receptors from the oviduct of the American alligator. | 1996 Dec |
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| Xenobiotic interaction with and alteration of channel catfish estrogen receptor. | 1997 Dec |
|
| Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells. | 1998 Jul |
|
| Differential estrogen receptor binding of estrogenic substances: a species comparison. | 2000 Nov 15 |
|
| Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens. | 2001 Mar |
|
| Screening of environmental contaminants for ecdysteroid agonist and antagonist activity using the Drosophila melanogaster B(II) cell in vitro assay. | 2001 Sep |
|
| Development of a fish reporter gene system for the assessment of estrogenic compounds and sewage treatment plant effluents. | 2002 Sep |
|
| In ovo exposure to o,p -DDE affects sexual development but not sexual differentiation in Japanese medaka (Oryzias latipes). | 2003 Jan |
|
| Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor. | 2003 Oct |
|
| Recombinant human estrogen, androgen and progesterone receptors for detection of potential endocrine disruptors. | 2004 Feb |
|
| Organochlorine micropollutants in the Jiulong River Estuary and Western Xiamen Sea, China. | 2005 |
|
| CAR and PXR: xenosensors of endocrine disrupters? | 2005 Aug 15 |
|
| Distribution and mass inventory of total dichlorodiphenyldichloroethylene in the water column of the southern California bight. | 2005 Nov 1 |
|
| Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: a potential novel mechanism of endocrine disruption. | 2006 Dec |
|
| Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | 2006 Nov |
|
| DDT- and DDE-induced disruption of ovarian steroidogenesis in prepubertal porcine ovarian follicles: a possible interaction with the main steroidogenic enzymes and estrogen receptor beta. | 2007 Dec |
|
| Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism. | 2008 Apr |
|
| Screening of some anti-progestin endocrine disruptors using a recombinant yeast based in vitro bioassay. | 2008 Apr |
|
| A novel pretreatment approach for fast determination of organochlorine pesticides in biotic samples. | 2008 May |
|
| Cytotoxicity and decreased corticosterone production in adrenocortical Y-1 cells by 3-methylsulfonyl-DDE and structurally related molecules. | 2009 Apr |
|
| Differential effects exerted on human mammary epithelial cells by environmentally relevant organochlorine pesticides either individually or in combination. | 2009 Aug 14 |
|
| Effects of o,p'-DDE, heptachlor, and 17beta-estradiol on vitellogenin gene expression and the growth hormone/insulin-like growth factor-I axis in the tilapia, Oreochromis mossambicus. | 2009 May |
|
| The influence of polychlorinated biphenyls (PCBs), dichlorodiphenyltrichloroethane (DDT) and its metabolite-dichlorodiphenyldichloroethylene (DDE) on mRNA expression for NP-I/OT and PGA, involved in oxytocin synthesis in bovine granulosa and luteal cells. | 2009 Nov |
|
| Comparison of relative binding affinities to fish and mammalian estrogen receptors: the regulatory implications. | 2010 Feb 15 |
|
| Differential effect of DDT, DDE, and DDD on COX-2 expression in the human trophoblast derived HTR-8/SVneo cells. | 2012 Nov |
|
| The organochlorine o,p'-DDT plays a role in coactivator-mediated MAPK crosstalk in MCF-7 breast cancer cells. | 2012 Sep |
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3424-82-6
Created by
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DM084YLQ1L
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DTXSID4022313
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222-318-0
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59908
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246598
Created by
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PARENT (METABOLITE)
SUBSTANCE RECORD
