O,P'-DDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H8Cl4
Molecular Weight	318.025
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

ClC(Cl)=C(C1=CC=C(Cl)C=C1)C2=C(Cl)C=CC=C2

InChI

InChIKey=ZDYJWDIWLRZXDB-UHFFFAOYSA-N

InChI=1S/C14H8Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8H

HIDE SMILES / InChI

Molecular Formula	C14H8Cl4
Molecular Weight	318.025
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Influence of chlorinated hydrocarbons, Hg2+ and methyl-Hg+ on steroid hormone receptors from eggshell gland mucosa of domestic fowls and ducks.	1991	2053848
Interaction of environmental chemicals with the estrogen and progesterone receptors from the oviduct of the American alligator.	1996 Dec	9118873
Xenobiotic interaction with and alteration of channel catfish estrogen receptor.	1997 Dec	9439733
Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells.	1998 Jul	9705896
Differential estrogen receptor binding of estrogenic substances: a species comparison.	2000 Nov 15	11162928
Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens.	2001 Mar	11258977
Screening of environmental contaminants for ecdysteroid agonist and antagonist activity using the Drosophila melanogaster B(II) cell in vitro assay.	2001 Sep	11521832
Development of a fish reporter gene system for the assessment of estrogenic compounds and sewage treatment plant effluents.	2002 Sep	12206426
In ovo exposure to o,p -DDE affects sexual development but not sexual differentiation in Japanese medaka (Oryzias latipes).	2003 Jan	12515675
Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.	2003 Oct	14565775
Recombinant human estrogen, androgen and progesterone receptors for detection of potential endocrine disruptors.	2004 Feb	14579009
Organochlorine micropollutants in the Jiulong River Estuary and Western Xiamen Sea, China.	2005	16291197
CAR and PXR: xenosensors of endocrine disrupters?	2005 Aug 15	16054614
Distribution and mass inventory of total dichlorodiphenyldichloroethylene in the water column of the southern California bight.	2005 Nov 1	16294851
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006 Nov	16497524
A novel pretreatment approach for fast determination of organochlorine pesticides in biotic samples.	2008 May	18437618
Cytotoxicity and decreased corticosterone production in adrenocortical Y-1 cells by 3-methylsulfonyl-DDE and structurally related molecules.	2009 Apr	18651133
Differential effects exerted on human mammary epithelial cells by environmentally relevant organochlorine pesticides either individually or in combination.	2009 Aug 14	19422813
Effects of o,p'-DDE, heptachlor, and 17beta-estradiol on vitellogenin gene expression and the growth hormone/insulin-like growth factor-I axis in the tilapia, Oreochromis mossambicus.	2009 May	19101654
The influence of polychlorinated biphenyls (PCBs), dichlorodiphenyltrichloroethane (DDT) and its metabolite-dichlorodiphenyldichloroethylene (DDE) on mRNA expression for NP-I/OT and PGA, involved in oxytocin synthesis in bovine granulosa and luteal cells.	2009 Nov	19383538
Comparison of relative binding affinities to fish and mammalian estrogen receptors: the regulatory implications.	2010 Feb 15	19913605
Differential effect of DDT, DDE, and DDD on COX-2 expression in the human trophoblast derived HTR-8/SVneo cells.	2012 Nov	23132776
The organochlorine o,p'-DDT plays a role in coactivator-mediated MAPK crosstalk in MCF-7 breast cancer cells.	2012 Sep	22609851

Substance Class	Chemical Created by `admin` on `Fri Dec 15 14:58:03 UTC 2023` Edited by `admin` on `Fri Dec 15 14:58:03 UTC 2023`
Record UNII	DM084YLQ1L
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

O,P'-DDE

Common Name

English

O,P'-DICHLORODIPHENYLDICHLOROETHYLENE

Common Name

English

2,4'-DICHLORODIPHENYLDICHLOROETHYLENE

Common Name

English

NSC-59908

Code

English

2-(2-CHLOROPHENYL)-2-(4-CHLOROPHENYL)-1,1-DICHLOROETHYLENE

Systematic Name

English

DDE, O,P'-

Common Name

English

ETHYLENE, 1,1-DICHLORO-2-(O-CHLOROPHENYL)-2-(P-CHLOROPHENYL)-

Common Name

English

2,4'-DDE

Common Name

English

BENZENE, 1-CHLORO-2-(2,2-DICHLORO-1-(4-CHLOROPHENYL)ETHENYL)-

Systematic Name

English

2,2-(2-CHLOROPHENYL-4'-CHLOROPHENYL)-1,1-DICHLOROETHENE

Systematic Name

English

1-CHLORO-2-(2,2-DICHLORO-1-(4-CHLOROPHENYL)ETHENYL)BENZENE

Systematic Name

English

1-CHLORO-2-(2,2-DICHLORO-1-(4-CHLOROPHENYL)VINYL)BENZENE

Systematic Name

English

Code System Code Type Description

CAS

3424-82-6