Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C12H24O11 |
| Molecular Weight | 344.3124 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 9 / 9 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)([C@H](O)CO)[C@H](O)[C@@H](O)CO
InChI
InChIKey=VQHSOMBJVWLPSR-WUJBLJFYSA-N
InChI=1S/C12H24O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h4-21H,1-3H2/t4-,5+,6+,7+,8+,9-,10+,11+,12+/m0/s1
DescriptionCurator's Comment: Description was created based on several sources, including
http://www.nutrientsreview.com/carbs/sugar-alcohols-maltitol.html | http://www.polyols-eu.com/maltitol
Curator's Comment: Description was created based on several sources, including
http://www.nutrientsreview.com/carbs/sugar-alcohols-maltitol.html | http://www.polyols-eu.com/maltitol
Maltitol is a sugar alcohol, or polyol. Small amounts of maltitol occur naturally in chicory leaves and in roasted malt. Commercially, maltitol
is produced from the starch of cereals such as corn, potatoes and wheat. Manufacturers use the catalytic hydrogenation of D-maltose to make a hydrogenated disaccharide consisting of a glucose molecule and a sorbitol molecule bound together. Maltitol is used as a low-calorie sweetener, humectant, thickening agent and texturizer in candies, chocolates, baked goods, ice creams, chewing gums and pan-coated tablets. In the European Union maltitol is labeled as E number E965.
CNS Activity
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Effects of oral administration of maltitol on plasma glucose, plasma sorbitol, and serum insulin levels in man. | 1986 Mar 17 |
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| Carbohydrate-controlled precipitation of apatite with coprecipitation of organic molecules in human saliva: stabilizing role of polyols. | 1989 Apr |
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| A high-performance liquid chromatography method for the analysis of picomole amounts of oligosaccharides. | 1989 May 1 |
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| Polyol-combinant saliva stimulants: a 4-month pilot study in young adults. | 1998 Apr |
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| Phosphorylation and metabolism of sucrose and its five linkage-isomeric alpha-D-glucosyl-D-fructoses by Klebsiella pneumoniae. | 2001 Mar 22 |
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| Interaction of methylparaben preservative with selected sugars and sugar alcohols. | 2002 Jul |
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| Sugar alcohols enhance calcium transport from rat small and large intestine epithelium in vitro. | 2002 Jun |
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| Plasticized waxy maize starch: effect of polyols and relative humidity on material properties. | 2002 Sep-Oct |
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| Health potential of polyols as sugar replacers, with emphasis on low glycaemic properties. | 2003 Dec |
|
| Cloning and characterization of two alpha-glucosidases from Bifidobacterium adolescentis DSM20083. | 2003 Mar |
|
| Chemoenzymatically synthesized glycoconjugate polymers. | 2003 Mar-Apr |
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| NMR and quantum chemical study on the OH...pi and CH...O interactions between trehalose and unsaturated fatty acids: implication for the mechanism of antioxidant function of trehalose. | 2003 Oct 22 |
|
| Alternative sugars as potential carriers for dry powder inhalations. | 2004 Feb 11 |
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| Characteristics of erythritol and formulation of a novel coating with erythritol termed thin-layer sugarless coating. | 2004 Jul 8 |
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| Molecular mobility in amorphous maltose and maltitol from phosphorescence of erythrosin B. | 2005 Aug 25 |
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| Dynamic site heterogeneity in amorphous maltose and maltitol from spectral heterogeneity in erythrosin B phosphorescence. | 2005 Dec 12 |
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| Combined NMR and quantum chemical studies on the interaction between trehalose and dienes relevant to the antioxidant function of trehalose. | 2005 Feb 24 |
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| Oxygen solubility and permeability of carbohydrates. | 2005 Jun 13 |
|
| Human gut microbiota does not ferment erythritol. | 2005 Nov |
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| The cytogenetic effects of food sweetener maltitol in human peripheral lymphocytes. | 2006 |
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| The effect of liquorice extract-containing starch gel on the amount and microbial composition of plaque. | 2006 Jun |
|
| Genetic requirements for growth of Escherichia coli K12 on methyl-alpha-D-glucopyranoside and the five alpha-D-glucosyl-D-fructose isomers of sucrose. | 2006 Jun 30 |
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| Medicinal carbon tablets for treatment of acetaminophen intoxication: adsorption characteristics of medicinal carbon powder and its tablets. | 2006 Mar |
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| Linear response of mutans streptococci to increasing frequency of xylitol chewing gum use: a randomized controlled trial [ISRCTN43479664]. | 2006 Mar 24 |
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| Considerations about the theoretically expected crushing strength of tablets from binary powder mixtures: double layer tablets versus arithmetic additivity rule. | 2006 Nov |
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| Decreased salivary uptake of [14C]-xylitol after a four-week xylitol chewing gum regimen. | 2007 |
|
| Improved postprandial response and feeling of satiety after consumption of low-calorie muffins with maltitol and high-amylose corn starch. | 2007 Aug |
|
| Suppressive effect of partially hydrolyzed guar gum on transitory diarrhea induced by ingestion of maltitol and lactitol in healthy humans. | 2007 Sep |
|
| Ecology of lactobacilli in the oral cavity: a review of literature. | 2008 |
|
| High pressure study on molecular mobility of leucrose. | 2008 Aug 28 |
|
| Impact of sugar replacers on cognitive performance and function in rats. | 2008 Nov |
|
| Standards of medical care in diabetes--2009. | 2009 Jan |
|
| Sugar alcohols, caries incidence, and remineralization of caries lesions: a literature review. | 2010 |
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| A randomized cross-over study to evaluate the swallow-enhancing and taste-masking properties of a novel coating for oral tablets. | 2010 Aug |
|
| [Preparation of orally disintegrating tablets for masking of unpleasant taste: comparison with corrective-adding methods]. | 2010 Jan |
|
| Standards of medical care in diabetes--2010. | 2010 Jan |
|
| Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509). | 2010 Nov 30 |
|
| [Comparative effects of the maltitol chewing gums on reducing plaque]. | 2010 Oct |
Patents
Sample Use Guides
5.0% maltitol for 8 weeks significantly suppressed weight gain, hepatic fatty degeneration, hyperglycemia, and hypercholesterolemia in a mouse high-fat diet model.
Route of Administration:
Oral
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CODEX ALIMENTARIUS (GSFA) |
INS-965(I)
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DSLD |
3248 (Number of products:4)
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JECFA EVALUATION |
INS-965(I)
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NCI_THESAURUS |
C283
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7971
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CHEMBL63558
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C010745
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209-567-0
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DTXSID0044444
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1374907
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1363049
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493591
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C77138
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D65DG142WK
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SUB12136MIG
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D65DG142WK
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MALTITOL
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585-88-6
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100000080142
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68428
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SUBSTANCE RECORD
