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Details

Stereochemistry ABSOLUTE
Molecular Formula C12H24O11
Molecular Weight 344.3124
Optical Activity UNSPECIFIED
Defined Stereocenters 9 / 9
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MALTITOL

SMILES

[H][C@@](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)([C@H](O)CO)[C@H](O)[C@@H](O)CO

InChI

InChIKey=VQHSOMBJVWLPSR-WUJBLJFYSA-N
InChI=1S/C12H24O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h4-21H,1-3H2/t4-,5+,6+,7+,8+,9-,10+,11+,12+/m0/s1

HIDE SMILES / InChI

Molecular Formula C12H24O11
Molecular Weight 344.3124
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 9 / 9
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Maltitol is a sugar alcohol, or polyol. Small amounts of maltitol occur naturally in chicory leaves and in roasted malt. Commercially, maltitol is produced from the starch of cereals such as corn, potatoes and wheat. Manufacturers use the catalytic hydrogenation of D-maltose to make a hydrogenated disaccharide consisting of a glucose molecule and a sorbitol molecule bound together. Maltitol is used as a low-calorie sweetener, humectant, thickening agent and texturizer in candies, chocolates, baked goods, ice creams, chewing gums and pan-coated tablets. In the European Union maltitol is labeled as E number E965.

CNS Activity

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
69.0 mM [Ki]

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
Unknown

PubMed

Sample Use Guides

In Vivo Use Guide
5.0% maltitol for 8 weeks significantly suppressed weight gain, hepatic fatty degeneration, hyperglycemia, and hypercholesterolemia in a mouse high-fat diet model.
Route of Administration: Oral
In Vitro Use Guide
Maltitol (1.25, 2.5, and 5 mg/mL) has a weak genotoxic potential and it appears non-cytotoxic to human peripheral lymphocytes in vitro.
Substance Class Chemical
Record UNII
D65DG142WK
Record Status Validated (UNII)
Record Version