DIMOXAPROST

Details

Stereochemistry	RACEMIC
Molecular Formula	C21H34O6
Molecular Weight	382.4911
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	2
Charge	0
Stereo Comments	RACEMIC ABOUT CYCLOPENTANE RING

SHOW SMILES / InChI

Structure Search

SMILES

CCOCC(C)(C)[C@@H](O)\C=C\[C@@H]1[C@@H](O)CC(=O)[C@H]1C\C=C/CCCC(O)=O

InChI

InChIKey=UJFDLBWYYFZXDS-LEENOTDESA-N

InChI=1S/C21H34O6/c1-4-27-14-21(2,3)19(24)12-11-16-15(17(22)13-18(16)23)9-7-5-6-8-10-20(25)26/h5,7,11-12,15-16,18-19,23-24H,4,6,8-10,13-14H2,1-3H3,(H,25,26)/b7-5-,12-11+/t15-,16-,18-,19-/m0/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6596097 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 444, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | Morton, I.K., Hall, J.M. (2012) Concise Dictionary of Pharmacological Agents, page 101, retrieved from: https://books.google.ru/books?id=tsjrCAAAQBAJ

Hoe 260 is a long-lasting and potent antisecretory and cytoprotective prostaglandin E2-analogue, having a favourable split between therapeutic gastric effects, effect on blood pressure and intestinal side effects. It is a prostanoid receptor agonist with antiulcerogenic activity.

Approval Year

PubMed

Title	Date	PubMed
Gastrointestinal and cardiovascular effects of the prostaglandin analogue Hoe 260.	1984	6596097

Name

Type

Language

DIMOXAPROST

Official Name

English

dimoxaprost [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C78568