DIMOXAPROST

Details

Stereochemistry	RACEMIC
Molecular Formula	C21H34O6
Molecular Weight	382.4911
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	2
Charge	0
Stereo Comments	RACEMIC ABOUT CYCLOPENTANE RING

SHOW SMILES / InChI

Structure Search

SMILES

CCOCC(C)(C)[C@@H](O)\C=C\[C@@H]1[C@@H](O)CC(=O)[C@H]1C\C=C/CCCC(O)=O

InChI

InChIKey=UJFDLBWYYFZXDS-LEENOTDESA-N

InChI=1S/C21H34O6/c1-4-27-14-21(2,3)19(24)12-11-16-15(17(22)13-18(16)23)9-7-5-6-8-10-20(25)26/h5,7,11-12,15-16,18-19,23-24H,4,6,8-10,13-14H2,1-3H3,(H,25,26)/b7-5-,12-11+/t15-,16-,18-,19-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C21H34O6
Molecular Weight	382.4911
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	2
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6596097 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 444, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | Morton, I.K., Hall, J.M. (2012) Concise Dictionary of Pharmacological Agents, page 101, retrieved from: https://books.google.ru/books?id=tsjrCAAAQBAJ

Hoe 260 is a long-lasting and potent antisecretory and cytoprotective prostaglandin E2-analogue, having a favourable split between therapeutic gastric effects, effect on blood pressure and intestinal side effects. It is a prostanoid receptor agonist with antiulcerogenic activity.

Approval Year

PubMed

Title	Date	PubMed
Gastrointestinal and cardiovascular effects of the prostaglandin analogue Hoe 260.	1984	6596097

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:33:07 GMT 2023` Edited by `admin` on `Fri Dec 15 16:33:07 GMT 2023`
Record UNII	D3R9B47JTE
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DIMOXAPROST

Official Name

English

dimoxaprost [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C78568