Details
Stereochemistry | ACHIRAL |
Molecular Formula | C10H14N2O |
Molecular Weight | 178.231 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC=CC(C)=C1NC(=O)CN
InChI
InChIKey=IXYVBZOSGGJWCW-UHFFFAOYSA-N
InChI=1S/C10H14N2O/c1-7-4-3-5-8(2)10(7)12-9(13)6-11/h3-5H,6,11H2,1-2H3,(H,12,13)
Approval Year
PubMed
Title | Date | PubMed |
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Involvement of liver carboxylesterases in the in vitro metabolism of lidocaine. | 2002 Jun |
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Chromatographic determination of free lidocaine and its active metabolites in plasma from patients under epidural anesthesia. | 2002 Nov |
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Effect of the CYP3A4 inhibitor erythromycin on the pharmacokinetics of lignocaine and its pharmacologically active metabolites in subjects with normal and impaired liver function. | 2003 Jan |
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Free lidocaine concentrations during continuous epidural anesthesia in geriatric patients. | 2003 May-Jun |
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Utility of nonaqueous capillary electrophoresis for the determination of lidocaine and its metabolites in human plasma: a comparison of ultraviolet and mass spectrometric detection. | 2004 |
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Cytochrome P450 1A2 is a major determinant of lidocaine metabolism in vivo: effects of liver function. | 2004 Jan |
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Effect of lidocaine on the minimum alveolar concentration of isoflurane in dogs. | 2004 Oct |
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Propofol does not inhibit lidocaine metabolism during epidural anesthesia. | 2004 Oct |
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Differential effect of chronic renal failure on the pharmacokinetics of lidocaine in patients receiving and not receiving hemodialysis. | 2006 Dec |
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Quantitative analysis of lignocaine and metabolites in equine urine and plasma by liquid chromatography-tandem mass spectrometry. | 2010 Jul 15 |
Patents
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D2D932W316
Created by
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18865-38-8
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357241
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87833
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DTXSID40876064
Created by
admin on Sat Dec 16 10:02:42 GMT 2023 , Edited by admin on Sat Dec 16 10:02:42 GMT 2023
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PARENT (METABOLITE LESS ACTIVE)
SUBSTANCE RECORD