| Stereochemistry | ABSOLUTE |
| Molecular Formula | C43H68O14 |
| Molecular Weight | 808.9916 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 18 / 18 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC[C@H](C)C(=O)O[C@H]1[C@H](O)[C@]2(COC(C)=O)[C@@H](O)C[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)C(O)=O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@@H]2CC1(C)C
InChI
InChIKey=IWLKKMZNFBKYCF-GAZXINLWSA-N
InChI=1S/C43H68O14/c1-10-21(2)36(53)57-34-33(50)43(20-54-22(3)45)24(17-38(34,4)5)23-11-12-26-39(6)15-14-28(55-37-31(49)29(47)30(48)32(56-37)35(51)52)40(7,19-44)25(39)13-16-41(26,8)42(23,9)18-27(43)46/h11,21,24-34,37,44,46-50H,10,12-20H2,1-9H3,(H,51,52)/t21-,24-,25+,26+,27-,28-,29-,30-,31+,32-,33-,34-,37+,39-,40-,41+,42+,43-/m0/s1
Gymnemic acid II is a glycoside isolated from the leaves of Gymnema sylvestre (Asclepiadaceae), it has being shown to be a glucose uptake inhibitor and to have a potent antidiabetic activity. Gymnemic acids are triterpene glycosides that selectively suppress taste responses to various sweet substances in humans.
Approval Year
PubMed
Patents
Sample Use Guides
0.5 mM of a solution of gymnemic acids I and II led a complete
suppression of sweetness induced by 0.4 mM sucrose. Application of a 1 mM solution of gymnemic acids I and II orally led to a complete suppression of sweetness induced by 0.2 and 0.4 M sucrose,
Route of Administration:
Oral
SUBSTANCE RECORD
