Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C43H68O14 |
| Molecular Weight | 808.9916 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 18 / 18 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]6(O[C@H]1CC[C@@]2(C)[C@@]([H])(CC[C@]3(C)[C@]2([H])CC=C4[C@]5([H])CC(C)(C)[C@@H](OC(=O)[C@@H](C)CC)[C@H](O)[C@]5(COC(C)=O)[C@@H](O)C[C@@]34C)[C@]1(C)CO)O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)C(O)=O
InChI
InChIKey=IWLKKMZNFBKYCF-GAZXINLWSA-N
InChI=1S/C43H68O14/c1-10-21(2)36(53)57-34-33(50)43(20-54-22(3)45)24(17-38(34,4)5)23-11-12-26-39(6)15-14-28(55-37-31(49)29(47)30(48)32(56-37)35(51)52)40(7,19-44)25(39)13-16-41(26,8)42(23,9)18-27(43)46/h11,21,24-34,37,44,46-50H,10,12-20H2,1-9H3,(H,51,52)/t21-,24-,25+,26+,27-,28-,29-,30-,31+,32-,33-,34-,37+,39-,40-,41+,42+,43-/m0/s1
| Molecular Formula | C43H68O14 |
| Molecular Weight | 808.9916 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 18 / 18 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/25056955 | https://www.ncbi.nlm.nih.gov/pubmed/26058590Curator's Comment: Description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/16508237
Sources: https://www.ncbi.nlm.nih.gov/pubmed/25056955 | https://www.ncbi.nlm.nih.gov/pubmed/26058590
Curator's Comment: Description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/16508237
Gymnemic acid II is a glycoside isolated from the leaves of Gymnema sylvestre (Asclepiadaceae), it has being shown to be a glucose uptake inhibitor and to have a potent antidiabetic activity. Gymnemic acids are triterpene glycosides that selectively suppress taste responses to various sweet substances in humans.
Approval Year
Sample Use Guides
0.5 mM of a solution of gymnemic acids I and II led a complete
suppression of sweetness induced by 0.4 mM sucrose. Application of a 1 mM solution of gymnemic acids I and II orally led to a complete suppression of sweetness induced by 0.2 and 0.4 M sucrose,
Route of Administration:
Oral
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 02:06:35 GMT 2023
by
admin
on
Sat Dec 16 02:06:35 GMT 2023
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| Record UNII |
CUN60G2ITS
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| Record Status |
Validated (UNII)
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| Record Version |
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DSLD |
2860 (Number of products:2)
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91617872
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CUN60G2ITS
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122144-48-3
Created by
admin on Sat Dec 16 02:06:35 GMT 2023 , Edited by admin on Sat Dec 16 02:06:35 GMT 2023
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