Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | 2C3F6O.3H2O |
| Molecular Weight | 386.0897 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O.O.O.FC(F)(F)C(=O)C(F)(F)F.FC(F)(F)C(=O)C(F)(F)F
InChI
InChIKey=VAIZVCMDJPBJCM-UHFFFAOYSA-N
InChI=1S/2C3F6O.3H2O/c2*4-2(5,6)1(10)3(7,8)9;;;/h;;3*1H2
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Trifluoromethyl ketone-based inhibitors of apoptosis in cerebellar granule neurons. | 2001 Nov |
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| Intermolecular Overhauser effects in fluoroalcohol solutions of cyclo-alanylglycine. | 2002 Aug 15 |
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| Environmental mimic of receptor interaction: conformational analysis of CCK-15 in solution. | 2002 Feb 14 |
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| 'Entourage' effects of N-acyl ethanolamines at human vanilloid receptors. Comparison of effects upon anandamide-induced vanilloid receptor activation and upon anandamide metabolism. | 2002 Jun |
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| Synthesis of a new potential tridentate anthracene ligand bearing deprotectable methoxymethoxy (OMOM) group at 1,8-positions: attempt to synthesize anionic hypervalent carbon compounds. | 2003 Aug 4 |
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| Design, synthesis, and biological evaluation of simplified alpha-keto heterocycle, trifluoromethyl ketone, and formyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylase. | 2003 Oct 1 |
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| The antimotility action of a trifluoromethyl ketone on some gram-negative bacteria. | 2004 |
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| Hexafluoroacetone as protecting and activating reagent: site-selective functionalization of iminodiacetic acid. | 2004 Dec |
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| Conformational study of fragments of envelope proteins (gp120: 254-274 and gp41: 519-541) of HIV-1 by NMR and MD simulations. | 2004 Jun |
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| Inhibitory action of a new proton pump inhibitor, trifluoromethyl ketone derivative, against the motility of clarithromycin-susceptible and-resistant Helicobacter pylori. | 2004 Jun |
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| Structure and solvation of melittin in hexafluoroacetone/water. | 2004 Jun 15 |
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| A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells. | 2005 Jul 15 |
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| Conformational equilibria in formic acid and the adduct of formic acid and hexafluoroacetone, HCO2C(CF3)2OH. | 2007 Mar 16 |
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| Hepatic sequestration of chlordecone and hexafluoroacetone evaluated by pharmacokinetic modeling. | 2007 May 5 |
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| Diethyl [2,2,2-trifluoro-1-phenyl-sulfonyl-amino-1-(trifluoro-meth-yl)eth-yl]phospho-nate. | 2008 Aug 1 |
|
| Trifluoromethyl ketones from enolizable carboxylic acids via enediolate trifluoroacetylation/decarboxylation. | 2008 Dec 5 |
|
| One-pot synthesis of 3-fluoro-4-(trifluoromethyl)quinolines from pentafluoropropen-2-ol and their molecular modification. | 2008 Feb 15 |
|
| Influence of sulfur oxidation state and steric bulk upon trifluoromethyl ketone (TFK) binding kinetics to carboxylesterases and fatty acid amide hydrolase (FAAH). | 2008 Feb 15 |
|
| Ligand-directed immobilization of proteins through an esterase 2 fusion tag studied by atomic force microscopy. | 2008 Jan 4 |
|
| Screening of the active site from water by the incoming ligand triggers catalysis and inhibition in serine proteases. | 2008 Mar |
|
| A novel protecting/activating strategy for beta-hydroxy acids and its use in convergent peptide synthesis. | 2008 Mar 21 |
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| Inhibition of cyclooxygenases 1 and 2 by the phospholipase-blocker, arachidonyl trifluoromethyl ketone. | 2008 Nov |
|
| Development and biological activity of a new antagonist of the pheromone of the codling moth Cydia pomonella. | 2009 Sep 23 |
|
| Mechanical properties of regenerated Bombyx mori silk fibers and recombinant silk fibers produced by transgenic silkworms. | 2010 |
|
| Application of spectroscopic methods for structural analysis of chitin and chitosan. | 2010 Apr 29 |
|
| Thermal chemistry and photochemistry of hexafluoroacetone on rutile TiO2(110). | 2010 Jul 28 |
|
| Identification of new non-carboxylic acid containing inhibitors of aldose reductase. | 2010 Jun 1 |
|
| Structural optimization of photoswitch ligands for surface attachment of alpha-chymotrypsin and regulation of its surface binding. | 2010 Jun 18 |
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DTXSID7025392
Created by
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3032602
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CU1NOZ8PS6
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13098-39-0
Created by
admin on Sat Dec 16 08:03:56 GMT 2023 , Edited by admin on Sat Dec 16 08:03:56 GMT 2023
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SUBSTANCE RECORD
