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Details

Stereochemistry ACHIRAL
Molecular Formula C24H24N6O2
Molecular Weight 428.4864
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of OLMESARTAN LACTONE

SMILES

CCCC1=NC2=C(N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NN=NN5)C(=O)OC2(C)C

InChI

InChIKey=JUQNVWFXORBZQJ-UHFFFAOYSA-N
InChI=1S/C24H24N6O2/c1-4-7-19-25-21-20(23(31)32-24(21,2)3)30(19)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22-26-28-29-27-22/h5-6,8-13H,4,7,14H2,1-3H3,(H,26,27,28,29)

HIDE SMILES / InChI
Olmesartan Lactone Impurity (Olmesartan EP Impurity B) is a cyclic ester impurity in commercial preparations of olmesartan medoxomil. Olmesartan medoxomil is an angiotensin II receptor antagonist, which is indicated for the treatment of hypertension.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Patents

Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
OLMESARTAN LACTONE
Common Name English
OLMESARTAN MEDOXOMIL IMPURITY B [EP IMPURITY]
Common Name English
OLMESARTAN MEDOXOMIL RELATED COMPOUND A
USP   USP-RS  
Common Name English
4H-FURO(3,4-D)IMIDAZOL-4-ONE, 3,6-DIHYDRO-6,6-DIMETHYL-2-PROPYL-3-((2'-(2H-TETRAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)METHYL)-
Systematic Name English
6,6-DIMETHYL-2-PROPYL-3-((2'-(1H-TETRAZOL-5-YL)BIPHENYL-4-YL)METHYL)-3,6-DIHYDRO-4H-FURO(3,4-D)IMIDAZOL-4-ONE
Systematic Name English
OLMESARTAN MEDOXOMIL RELATED COMPOUND A [USP-RS]
Common Name English
OLMESARTAN MEDOXOMIL RELATED COMPOUND A [USP IMPURITY]
Common Name English
Code System Code Type Description
RS_ITEM_NUM
1478378
Created by admin on Sat Dec 16 07:54:01 GMT 2023 , Edited by admin on Sat Dec 16 07:54:01 GMT 2023
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EPA CompTox
DTXSID90233966
Created by admin on Sat Dec 16 07:54:01 GMT 2023 , Edited by admin on Sat Dec 16 07:54:01 GMT 2023
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CAS
849206-43-5
Created by admin on Sat Dec 16 07:54:01 GMT 2023 , Edited by admin on Sat Dec 16 07:54:01 GMT 2023
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PUBCHEM
71751323
Created by admin on Sat Dec 16 07:54:01 GMT 2023 , Edited by admin on Sat Dec 16 07:54:01 GMT 2023
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FDA UNII
CML390S782
Created by admin on Sat Dec 16 07:54:01 GMT 2023 , Edited by admin on Sat Dec 16 07:54:01 GMT 2023
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