OLMESARTAN LACTONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C24H24N6O2
Molecular Weight	428.4864
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCC1=NC2=C(N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NN=NN5)C(=O)OC2(C)C

InChI

InChIKey=JUQNVWFXORBZQJ-UHFFFAOYSA-N

InChI=1S/C24H24N6O2/c1-4-7-19-25-21-20(23(31)32-24(21,2)3)30(19)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22-26-28-29-27-22/h5-6,8-13H,4,7,14H2,1-3H3,(H,26,27,28,29)

HIDE SMILES / InChI

Molecular Formula	C24H24N6O2
Molecular Weight	428.4864
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.google.com/patents/US8933241

Olmesartan Lactone Impurity (Olmesartan EP Impurity B) is a cyclic ester impurity in commercial preparations of olmesartan medoxomil. Olmesartan medoxomil is an angiotensin II receptor antagonist, which is indicated for the treatment of hypertension.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 07:54:01 UTC 2023` Edited by `admin` on `Sat Dec 16 07:54:01 UTC 2023`
Record UNII	CML390S782
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

OLMESARTAN LACTONE

Common Name

English

OLMESARTAN MEDOXOMIL IMPURITY B [EP IMPURITY]

Common Name

English

OLMESARTAN MEDOXOMIL RELATED COMPOUND A

Common Name

English

4H-FURO(3,4-D)IMIDAZOL-4-ONE, 3,6-DIHYDRO-6,6-DIMETHYL-2-PROPYL-3-((2'-(2H-TETRAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)METHYL)-

Systematic Name

English

6,6-DIMETHYL-2-PROPYL-3-((2'-(1H-TETRAZOL-5-YL)BIPHENYL-4-YL)METHYL)-3,6-DIHYDRO-4H-FURO(3,4-D)IMIDAZOL-4-ONE

Systematic Name

English

OLMESARTAN MEDOXOMIL RELATED COMPOUND A [USP-RS]

Common Name

English

OLMESARTAN MEDOXOMIL RELATED COMPOUND A [USP IMPURITY]

Common Name

English

Code System Code Type Description

RS_ITEM_NUM

1478378