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Details

Stereochemistry RACEMIC
Molecular Formula C20H25NS
Molecular Weight 311.484
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TALSUPRAM

SMILES

CNCCCC1(SC(C)(C)C2=CC=CC=C12)C3=CC=CC=C3

InChI

InChIKey=FKHYYOUFMJBLAF-UHFFFAOYSA-N
InChI=1S/C20H25NS/c1-19(2)17-12-7-8-13-18(17)20(22-19,14-9-15-21-3)16-10-5-4-6-11-16/h4-8,10-13,21H,9,14-15H2,1-3H3

HIDE SMILES / InChI
Targets

Targets

Primary TargetPharmacologyConditionPotency
0.79 nM [IC50]
9300.0 nM [IC50]
850.0 nM [IC50]
0.79 nM [IC50]
PubMed

PubMed

TitleDatePubMed
Synthesis and biological evaluation of [11C]talopram and [11C]talsupram: candidate PET ligands for the norepinephrine transporter.
2004 Aug
Synthesis and positron emission tomography evaluation of three norepinephrine transporter radioligands: [C-11]desipramine, [C-11]talopram and [C-11]talsupram.
2006 Jan-Feb
Noradrenergic mechanisms in cocaine-induced reinstatement of drug seeking in squirrel monkeys.
2007 Aug
Name Type Language
TALSUPRAM
INN  
INN  
Official Name English
talsupram [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C265
Created by admin on Fri Dec 15 18:34:28 GMT 2023 , Edited by admin on Fri Dec 15 18:34:28 GMT 2023
Code System Code Type Description
MESH
C001750
Created by admin on Fri Dec 15 18:34:28 GMT 2023 , Edited by admin on Fri Dec 15 18:34:28 GMT 2023
PRIMARY
FDA UNII
C6Z73MW6CR
Created by admin on Fri Dec 15 18:34:28 GMT 2023 , Edited by admin on Fri Dec 15 18:34:28 GMT 2023
PRIMARY
WIKIPEDIA
Talsupram
Created by admin on Fri Dec 15 18:34:28 GMT 2023 , Edited by admin on Fri Dec 15 18:34:28 GMT 2023
PRIMARY
ChEMBL
CHEMBL52247
Created by admin on Fri Dec 15 18:34:28 GMT 2023 , Edited by admin on Fri Dec 15 18:34:28 GMT 2023
PRIMARY
DRUG BANK
DB09191
Created by admin on Fri Dec 15 18:34:28 GMT 2023 , Edited by admin on Fri Dec 15 18:34:28 GMT 2023
PRIMARY
EPA CompTox
DTXSID50864992
Created by admin on Fri Dec 15 18:34:28 GMT 2023 , Edited by admin on Fri Dec 15 18:34:28 GMT 2023
PRIMARY
SMS_ID
100000083209
Created by admin on Fri Dec 15 18:34:28 GMT 2023 , Edited by admin on Fri Dec 15 18:34:28 GMT 2023
PRIMARY
PUBCHEM
33014
Created by admin on Fri Dec 15 18:34:28 GMT 2023 , Edited by admin on Fri Dec 15 18:34:28 GMT 2023
PRIMARY
EVMPD
SUB10815MIG
Created by admin on Fri Dec 15 18:34:28 GMT 2023 , Edited by admin on Fri Dec 15 18:34:28 GMT 2023
PRIMARY
INN
3076
Created by admin on Fri Dec 15 18:34:28 GMT 2023 , Edited by admin on Fri Dec 15 18:34:28 GMT 2023
PRIMARY
CAS
21489-20-3
Created by admin on Fri Dec 15 18:34:28 GMT 2023 , Edited by admin on Fri Dec 15 18:34:28 GMT 2023
PRIMARY
NCI_THESAURUS
C75180
Created by admin on Fri Dec 15 18:34:28 GMT 2023 , Edited by admin on Fri Dec 15 18:34:28 GMT 2023
PRIMARY