Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C15H16N2O |
| Molecular Weight | 240.3003 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC(=CC(C)=C1)C(=O)NCC2=CC=NC=C2
InChI
InChIKey=JROSDBYIFZWPBP-UHFFFAOYSA-N
InChI=1S/C15H16N2O/c1-11-7-12(2)9-14(8-11)15(18)17-10-13-3-5-16-6-4-13/h3-9H,10H2,1-2H3,(H,17,18)
Picobenzide is a synthetic product which is of therapeutic interest owing to its neuroleptic, anti-inflammatory and spasmolytic action and because its properties are similar to those of the phenotiazines. The product is largely metabolized into the N-oxide form and is also partially eliminated in urine in an unaltered state.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| [Comparative study of the pharmacological activity of N-(4-picolyl)-3,5-dimethylbenzamide (M-14012-4) and its N-oxide metabolite (M-3312-4). New pharmacological aspects]. | 1979 Dec |
|
| [Comparative study of the central effects of M-14012-A and SKF-525-A in rodents]. | 1983 Aug |
|
| 'In vitro' metabolism of N-picolyl-3,5-dimethylbenzamides. | 1986 Apr-Jun |
|
| Isolation and identification of the N-oxide metabolite of picobenzide in human urine. | 1986 Jan-Mar |
|
| Study of the disposition kinetics of the N-oxide-derivative: a metabolite of picobenzide. | 1989 Jan-Mar |
|
| Synthesis and biological activity of picobenzide (3,5-dimethyl-N-(pyridin-4-ylmethyl)benzamide) analogues as potential antipsychotic agents. | 2005 |
| Name | Type | Language | ||
|---|---|---|---|---|
|
Official Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
NCI_THESAURUS |
C29710
Created by
admin on Fri Dec 15 16:09:57 GMT 2023 , Edited by admin on Fri Dec 15 16:09:57 GMT 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
C016938
Created by
admin on Fri Dec 15 16:09:57 GMT 2023 , Edited by admin on Fri Dec 15 16:09:57 GMT 2023
|
PRIMARY | |||
|
40146
Created by
admin on Fri Dec 15 16:09:57 GMT 2023 , Edited by admin on Fri Dec 15 16:09:57 GMT 2023
|
PRIMARY | |||
|
100000081919
Created by
admin on Fri Dec 15 16:09:57 GMT 2023 , Edited by admin on Fri Dec 15 16:09:57 GMT 2023
|
PRIMARY | |||
|
CHEMBL1581974
Created by
admin on Fri Dec 15 16:09:57 GMT 2023 , Edited by admin on Fri Dec 15 16:09:57 GMT 2023
|
PRIMARY | |||
|
C76443
Created by
admin on Fri Dec 15 16:09:57 GMT 2023 , Edited by admin on Fri Dec 15 16:09:57 GMT 2023
|
PRIMARY | |||
|
4674
Created by
admin on Fri Dec 15 16:09:57 GMT 2023 , Edited by admin on Fri Dec 15 16:09:57 GMT 2023
|
PRIMARY | |||
|
DTXSID10199792
Created by
admin on Fri Dec 15 16:09:57 GMT 2023 , Edited by admin on Fri Dec 15 16:09:57 GMT 2023
|
PRIMARY | |||
|
SUB09814MIG
Created by
admin on Fri Dec 15 16:09:57 GMT 2023 , Edited by admin on Fri Dec 15 16:09:57 GMT 2023
|
PRIMARY | |||
|
C46317G8F0
Created by
admin on Fri Dec 15 16:09:57 GMT 2023 , Edited by admin on Fri Dec 15 16:09:57 GMT 2023
|
PRIMARY | |||
|
51832-87-2
Created by
admin on Fri Dec 15 16:09:57 GMT 2023 , Edited by admin on Fri Dec 15 16:09:57 GMT 2023
|
PRIMARY |
ACTIVE MOIETY
