Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H8N2O2 |
| Molecular Weight | 152.1506 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CNC(=O)C1=CNC(=O)C=C1
InChI
InChIKey=NBUNJDAKVMXXEF-UHFFFAOYSA-N
InChI=1S/C7H8N2O2/c1-8-7(11)5-2-3-6(10)9-4-5/h2-4H,1H3,(H,8,11)(H,9,10)
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Accumulation of plasma N-methyl-2-pyridone-5-carboxamide in patients with chronic renal failure. | 2002 Feb |
|
| N-methyl-2-pyridone-5-carboxamide: a novel uremic toxin? | 2003 May |
|
| The age-related increase in N-methyl-2-pyridone-5-carboxamide (NAD catabolite) in human plasma. | 2004 Dec |
|
| Disturbances of purine nucleotide metabolism in uremia. | 2004 Sep |
|
| Accumulation of poly(ADP-ribose) polymerase inhibitors in children with chronic renal failure. | 2006 Jun |
|
| Relationship between uremic toxins and oxidative stress in patients with chronic renal failure. | 2007 |
|
| Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation. | 2007 Aug |
|
| Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites. | 2007 Jun |
|
| The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet. | 2007 Sep |
|
| Nicotinamide metabolites accumulate in the tissues of uremic rats. | 2008 Jan |
|
| Are so-called uremic toxins always toxic? | 2008 Jan |
|
| Development of a hydrophilic liquid interaction chromatography-high-performance liquid chromatography-tandem mass spectrometry based stable isotope dilution analysis and pharmacokinetic studies on bioactive pyridines in human plasma and urine after coffee consumption. | 2010 Feb 15 |
|
| Urinary metabolic phenotyping differentiates children with autism from their unaffected siblings and age-matched controls. | 2010 Jun 4 |
|
| Metabonomics study of urine and plasma in depression and excess fatigue rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry. | 2010 May |
|
| Simultaneous determination of niacin and its metabolites--nicotinamide, nicotinuric acid and N-methyl-2-pyridone-5-carboxamide--in human plasma by LC-MS/MS and its application to a human pharmacokinetic study. | 2010 Oct |
|
| Distribution of purine nucleotides in uremic fluids and tissues. | 2010 Sep |
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1007-18-7
Created by
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C2M49S613F
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DTXSID70143458
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C005211
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27410
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70510
Created by
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SUBSTANCE RECORD
