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Details

Stereochemistry ACHIRAL
Molecular Formula C7H8N2O2
Molecular Weight 152.1506
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1,6-DIHYDRO-N-METHYL-6-OXONICOTINAMIDE

SMILES

CNC(=O)C1=CNC(=O)C=C1

InChI

InChIKey=NBUNJDAKVMXXEF-UHFFFAOYSA-N
InChI=1S/C7H8N2O2/c1-8-7(11)5-2-3-6(10)9-4-5/h2-4H,1H3,(H,8,11)(H,9,10)

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
N-methyl-2-pyridone-5-carboxamide: a novel uremic toxin?
2003 May
The age-related increase in N-methyl-2-pyridone-5-carboxamide (NAD catabolite) in human plasma.
2004 Dec
Disturbances of purine nucleotide metabolism in uremia.
2004 Sep
Accumulation of poly(ADP-ribose) polymerase inhibitors in children with chronic renal failure.
2006 Jun
Relationship between uremic toxins and oxidative stress in patients with chronic renal failure.
2007
A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human.
2007 Apr 24
Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation.
2007 Aug
Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites.
2007 Jun
The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet.
2007 Sep
Nicotinamide metabolites accumulate in the tissues of uremic rats.
2008 Jan
Are so-called uremic toxins always toxic?
2008 Jan
Urinary metabolic phenotyping differentiates children with autism from their unaffected siblings and age-matched controls.
2010 Jun 4
Metabonomics study of urine and plasma in depression and excess fatigue rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry.
2010 May
Simultaneous determination of niacin and its metabolites--nicotinamide, nicotinuric acid and N-methyl-2-pyridone-5-carboxamide--in human plasma by LC-MS/MS and its application to a human pharmacokinetic study.
2010 Oct
Distribution of purine nucleotides in uremic fluids and tissues.
2010 Sep
Name Type Language
1,6-DIHYDRO-N-METHYL-6-OXONICOTINAMIDE
Systematic Name English
N'-METHYL-2-PYRIDONE-5-CARBOXAMIDE
Common Name English
NICOTINAMIDE, 1,6-DIHYDRO-N-METHYL-6-OXO-
Systematic Name English
3-PYRIDINECARBOXAMIDE, 1,6-DIHYDRO-N-METHYL-6-OXO-
Systematic Name English
Code System Code Type Description
CAS
1007-18-7
Created by admin on Fri Dec 15 17:48:12 GMT 2023 , Edited by admin on Fri Dec 15 17:48:12 GMT 2023
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FDA UNII
C2M49S613F
Created by admin on Fri Dec 15 17:48:12 GMT 2023 , Edited by admin on Fri Dec 15 17:48:12 GMT 2023
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EPA CompTox
DTXSID70143458
Created by admin on Fri Dec 15 17:48:12 GMT 2023 , Edited by admin on Fri Dec 15 17:48:12 GMT 2023
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MESH
C005211
Created by admin on Fri Dec 15 17:48:12 GMT 2023 , Edited by admin on Fri Dec 15 17:48:12 GMT 2023
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CHEBI
27410
Created by admin on Fri Dec 15 17:48:12 GMT 2023 , Edited by admin on Fri Dec 15 17:48:12 GMT 2023
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PUBCHEM
70510
Created by admin on Fri Dec 15 17:48:12 GMT 2023 , Edited by admin on Fri Dec 15 17:48:12 GMT 2023
PRIMARY