1,6-DIHYDRO-N-METHYL-6-OXONICOTINAMIDE

CNC(=O)C1=CNC(=O)C=C1

InChIKey=NBUNJDAKVMXXEF-UHFFFAOYSA-N

InChI=1S/C7H8N2O2/c1-8-7(11)5-2-3-6(10)9-4-5/h2-4H,1H3,(H,8,11)(H,9,10)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Accumulation of plasma N-methyl-2-pyridone-5-carboxamide in patients with chronic renal failure.	2002 Feb	11952169
Accumulation of poly(ADP-ribose) polymerase inhibitors in children with chronic renal failure.	2006 Jun	16604373
A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human.	2007 Apr 24	17190852
Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation.	2007 Aug	17725178
Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites.	2007 Jun	17463214
Are so-called uremic toxins always toxic?	2008 Jan	18089437
Metabonomics study of urine and plasma in depression and excess fatigue rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry.	2010 May	20567771
Simultaneous determination of niacin and its metabolites--nicotinamide, nicotinuric acid and N-methyl-2-pyridone-5-carboxamide--in human plasma by LC-MS/MS and its application to a human pharmacokinetic study.	2010 Oct	20853461
Distribution of purine nucleotides in uremic fluids and tissues.	2010 Sep	20797575

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:48:12 GMT 2023` Edited by `admin` on `Fri Dec 15 17:48:12 GMT 2023`
Record UNII	C2M49S613F
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

1,6-DIHYDRO-N-METHYL-6-OXONICOTINAMIDE

Systematic Name

English

N'-METHYL-2-PYRIDONE-5-CARBOXAMIDE

Common Name

English

NICOTINAMIDE, 1,6-DIHYDRO-N-METHYL-6-OXO-

Systematic Name

English

3-PYRIDINECARBOXAMIDE, 1,6-DIHYDRO-N-METHYL-6-OXO-

Systematic Name

English

Code System Code Type Description

CAS

1007-18-7