1,6-DIHYDRO-N-METHYL-6-OXONICOTINAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H8N2O2
Molecular Weight	152.1506
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 1,6-DIHYDRO-N-METHYL-6-OXONICOTINAMIDE

Structure Search

SMILES

CNC(=O)C1=CNC(=O)C=C1

InChI

InChIKey=NBUNJDAKVMXXEF-UHFFFAOYSA-N

InChI=1S/C7H8N2O2/c1-8-7(11)5-2-3-6(10)9-4-5/h2-4H,1H3,(H,8,11)(H,9,10)

HIDE SMILES / InChI

Molecular Formula	C7H8N2O2
Molecular Weight	152.1506
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Simultaneous determination of niacin and its metabolites--nicotinamide, nicotinuric acid and N-methyl-2-pyridone-5-carboxamide--in human plasma by LC-MS/MS and its application to a human pharmacokinetic study.	2010-10	20853461
Distribution of purine nucleotides in uremic fluids and tissues.	2010-09	20797575
Urinary metabolic phenotyping differentiates children with autism from their unaffected siblings and age-matched controls.	2010-06-04	20337404
Metabonomics study of urine and plasma in depression and excess fatigue rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry.	2010-05	20567771
Development of a hydrophilic liquid interaction chromatography-high-performance liquid chromatography-tandem mass spectrometry based stable isotope dilution analysis and pharmacokinetic studies on bioactive pyridines in human plasma and urine after coffee consumption.	2010-02-15	20073472
Nicotinamide metabolites accumulate in the tissues of uremic rats.	2008-01	18089445
Are so-called uremic toxins always toxic?	2008-01	18089437
The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet.	2007-09	17571283
Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation.	2007-08	17725178
Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites.	2007-06	17463214
A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human.	2007-04-24	17190852
Relationship between uremic toxins and oxidative stress in patients with chronic renal failure.	2007	17469035
Accumulation of poly(ADP-ribose) polymerase inhibitors in children with chronic renal failure.	2006-06	16604373
The age-related increase in N-methyl-2-pyridone-5-carboxamide (NAD catabolite) in human plasma.	2004-12	15663182
Disturbances of purine nucleotide metabolism in uremia.	2004-09	15490415
N-methyl-2-pyridone-5-carboxamide: a novel uremic toxin?	2003-05	12694300
Accumulation of plasma N-methyl-2-pyridone-5-carboxamide in patients with chronic renal failure.	2002-02	11952169

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:53:10 GMT 2025` Edited by `admin` on `Mon Mar 31 18:53:10 GMT 2025`
Record UNII	C2M49S613F
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1,6-DIHYDRO-N-METHYL-6-OXONICOTINAMIDE

Systematic Name

English

N'-METHYL-2-PYRIDONE-5-CARBOXAMIDE

Preferred Name

English

NICOTINAMIDE, 1,6-DIHYDRO-N-METHYL-6-OXO-

Systematic Name

English

3-PYRIDINECARBOXAMIDE, 1,6-DIHYDRO-N-METHYL-6-OXO-

Systematic Name

English

Code System Code Type Description

CAS

1007-18-7