Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | Na.HO4S |
| Molecular Weight | 120.06 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].OS([O-])(=O)=O
InChI
InChIKey=WBHQBSYUUJJSRZ-UHFFFAOYSA-M
InChI=1S/Na.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+1;/p-1
SULFATE (as sodium sulfate, potassium sulfate, and magnesium sulfate) is a component of SUPREP Bowel Prep Kit. It is an osmotic laxative indicated for cleansing of the colon in preparation for colonoscopy in adults. Sulfate salts provide sulfate anions, which are poorly absorbed. The osmotic effect of unabsorbed sulfate anions and the associated cations causes water to be retained within the gastrointestinal tract. SUPREP Bowel Prep Kit, when ingested with a large volume of water, produces copious watery diarrhea.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Management of autonomic dysfunction in severe tetanus: the use of magnesium sulphate and clonidine. | 1990 |
|
| Patterns of sulphation in heparan sulphate: polymorphism based on a common structural theme. | 1992 Apr |
|
| Heparan sulphate in the binding and activation of basic fibroblast growth factor. | 1992 Dec |
|
| Death by tanning--a case of fatal basic chromium sulphate poisoning. | 1994 |
|
| Renal and small intestinal sodium-dependent symporters of phosphate and sulphate. | 1994 Nov |
|
| Dextran sulphate induces a PKC and actin independent internalisation of CD4. | 1994 Sep |
|
| Malaria during pregnancy: parasites, antibodies and chondroitin sulphate A. | 1999 Aug |
|
| Heparan sulphate. Regulation of growth factors in the mammary gland. | 2000 |
|
| Magnesium sulphate versus phenytoin for eclampsia. | 2000 |
|
| Specificities of heparan sulphate proteoglycans in developmental processes. | 2000 Apr 13 |
|
| Magnesium sulphate for eclampsia: putting the evidence into clinical practice. | 2000 Jun |
|
| Herpes simplex virus: discovering the link between heparan sulphate and hereditary bone tumours. | 2000 Nov-Dec |
|
| Magnesium sulphate for preventing preterm birth in threatened preterm labour. | 2002 |
|
| Chondroitin sulphate proteoglycans in the CNS injury response. | 2002 |
|
| [Skin patch test with nickel sulphate--an attempt of broader interpretation of the results]. | 2002 Aug |
|
| Dermatan sulphate as an antithrombotic drug. | 2002 Sep-Dec |
|
| Magnesium sulphate versus phenytoin for eclampsia. | 2003 |
|
| Hepatocyte growth factor/scatter factor and its interaction with heparan sulphate and dermatan sulphate. | 2003 Apr |
|
| Heparan sulphate proteoglycans in Alzheimer's disease and amyloid-related disorders. | 2003 Aug |
|
| Are low dehydroepiandrosterone sulphate levels predictive for cardiovascular diseases? A review of prospective and retrospective studies. | 2003 Oct |
|
| Characterization of the Herpesvirus saimiri Orf51 protein. | 2004 Aug 15 |
|
| The SLC13 gene family of sodium sulphate/carboxylate cotransporters. | 2004 Feb |
|
| Chondroitin sulphate proteoglycans: preventing plasticity or protecting the CNS? | 2004 Jan |
|
| Molecular recognition by LARGE is essential for expression of functional dystroglycan. | 2004 Jun 25 |
|
| [The extracellular matrix of the central nervous system: chondroitin sulphate type proteoglycans and neural repair]. | 2004 May 1-15 |
|
| Epidemiology of 377 patients with chemical burns in Guangdong province. | 2004 Sep |
|
| Biotechnological engineering of heparin/heparan sulphate: a novel area of multi-target drug discovery. | 2005 |
|
| Heparan sulphate proteoglycans: the sweet side of development. | 2005 Jul |
|
| Chondroitin sulphate: antioxidant properties and beneficial effects. | 2006 Dec |
|
| Heparin/heparan sulphate binding in the TGF-beta cytokine superfamily. | 2006 Jun |
|
| The role of heparan sulphate proteoglycans in angiogenesis. | 2006 Jun |
|
| Insights into the role of heparan sulphate in fibroblast growth factor signalling. | 2006 Jun |
|
| Signalling by HGF/SF and Met: the role of heparan sulphate co-receptors. | 2006 Jun |
|
| Dietary acidification enhances phosphorus digestibility but decreases H+/K+-ATPase expression in rainbow trout. | 2006 Oct |
|
| The role of heparan sulphate in inflammation. | 2006 Sep |
|
| [Therapy of osteoarthritis crystalline glucosamine sulphate/a review of the clinical effcacy]. | 2007 |
|
| Heparan sulphate proteoglycans fine-tune mammalian physiology. | 2007 Apr 26 |
|
| Evaluation of formocresol versus ferric sulphate primary molar pulpotomy: a systematic review and meta-analysis. | 2007 Oct |
|
| Cholesterol sulfate as a potential inhibitor of hepatitis C virus NS3 helicase. | 2014 Apr |
Patents
Sample Use Guides
Split-Dose (2-Day) Regimen:
The evening before colonoscopy: dilute one bottle with water to a total volume of 16 oz. (up to the fill line) and drink the entire amount. Drink 32 ounces of water over the next hour.
Next morning: repeat both steps using the second bottle. Complete preparation at least 2 hours before colonoscopy or as directed by a physician.
Route of Administration:
Oral
| Name | Type | Language | ||
|---|---|---|---|---|
|
Official Name | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Code | English | ||
|
Code | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
JECFA EVALUATION |
INS-514(II)
Created by
admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
|
||
|
EPA PESTICIDE CODE |
73201
Created by
admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
|
||
|
CODEX ALIMENTARIUS (GSFA) |
INS-514(II)
Created by
admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
DTXSID3033983
Created by
admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
|
PRIMARY | |||
|
BU8V88OWIQ
Created by
admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
|
PRIMARY | |||
|
m9992
Created by
admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
|
PRIMARY | Merck Index | ||
|
3
Created by
admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
|
PRIMARY | |||
|
1367207
Created by
admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
|
PRIMARY | RxNorm | ||
|
C45678
Created by
admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
|
CONCEPT | Industrial Aid | ||
|
516919
Created by
admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
|
PRIMARY | |||
|
C012036
Created by
admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
|
PRIMARY | |||
|
SODIUM BISULFATE
Created by
admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
|
PRIMARY | |||
|
231-665-7
Created by
admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
|
PRIMARY | |||
|
71192
Created by
admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
|
PRIMARY | |||
|
BU8V88OWIQ
Created by
admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
|
PRIMARY | |||
|
C77494
Created by
admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
|
PRIMARY | |||
|
7681-38-1
Created by
admin on Fri Dec 15 15:58:34 GMT 2023 , Edited by admin on Fri Dec 15 15:58:34 GMT 2023
|
PRIMARY |
SUBSTANCE RECORD
