5-FLUOROURIDINE MONOPHOSPHATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C9H12FN2O9P
Molecular Weight	342.1717
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 5-FLUOROURIDINE MONOPHOSPHATE

Structure Search

SMILES

O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(O)=O)N2C=C(F)C(=O)NC2=O

InChI

InChIKey=RNBMPPYRHNWTMA-UAKXSSHOSA-N

InChI=1S/C9H12FN2O9P/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(21-8)2-20-22(17,18)19/h1,4-6,8,13-14H,2H2,(H,11,15,16)(H2,17,18,19)/t4-,5-,6-,8-/m1/s1

HIDE SMILES / InChI

Description
Sources: https://www.ema.europa.eu/en/medicines/human/paediatric-investigation-plans/flosfluridine-tidoxil | https://adisinsight.springer.com/drugs/800019549

Flosfluridine tidoxil, a thymidylate synthase inhibitor that was developed for the treatment of actinic keratosis and solid tumors, e.g. breast and colorectal cancers. These studies were suspended and information about the further development of this drug is not available.

Originator

Approval Year

Name

Type

Language

5'-URIDYLIC ACID, 5-FLUORO-

Preferred Name

English

5-FLUOROURIDINE MONOPHOSPHATE

Systematic Name

English

5-FLUOROURIDINE 5'-MONOPHOSPHATE

Systematic Name

English

5-FLUOROURIDYLIC ACID

Common Name

English

Code System Code Type Description

PUBCHEM

150856