U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C4H8O2
Molecular Weight 88.1051
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1,3-DIOXANE

SMILES

C1COCOC1

InChI

InChIKey=VDFVNEFVBPFDSB-UHFFFAOYSA-N
InChI=1S/C4H8O2/c1-2-5-4-6-3-1/h1-4H2

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Split--pool synthesis of 1,3-dioxanes leading to arrayed stock solutions of single compounds sufficient for multiple phenotypic and protein-binding assays.
2001 Feb 28
Simultaneous discrimination of diastereotopic groups and faces: the first example in intramolecular [3+2] and [2+2+1] cycloaddition reactions.
2001 Jun 1
Electronic delocalization contribution to the anomeric effect evaluated by computational methods.
2001 May 4
Effect of geminal substitution on the strain energy of dioxiranes. Origin of the low ring strain of dimethyldioxirane.
2002 May 31
Structural biasing elements for in-cell histone deacetylase paralog selectivity.
2003 May 14
Modular synthesis and preliminary biological evaluation of stereochemically diverse 1,3-dioxanes.
2004 Sep
Relationships between the structure of dexoxadrol and etoxadrol analogues and their NMDA receptor affinity.
2006
5,5-Bis(hydroxy-meth-yl)-2-phenyl-1,3-dioxane.
2008 Jul 19
2,3:4,6-Di-O-isopropylidene-alpha-L-sorbofuranose and 2,3-O-isopropylidene-alpha-L-sorbofuranose.
2009 Apr
7,14-Bis(4-methoxy-phen-yl)-11,11-dimethyl-1,4,10,12-tetra-oxa-dispiro-[4.2.5.2]penta-decane-9,13-dione.
2009 Apr 18
7,14-Bis(4-bromo-phen-yl)-2,11,11-trimethyl-1,4,10,12-tetra-oxa-dispiro-[4.2.5.2]penta-decane-9,13-dione.
2009 Apr 30
2,2-Dimethyl-5-triphenyl-methyl-1,3-dioxane.
2009 Jan 14
Biodegradation of 1,4-dioxane and transformation of related cyclic compounds by a newly isolated Mycobacterium sp. PH-06.
2009 Jul
3-(2-Furylmethyl-ene)-1,5-dioxaspiro-[5.5]undecane-2,4-dione.
2009 Jul 15
Synthesis of uracil nucleotide analogs with a modified, acyclic ribose moiety as P2Y(2) receptor antagonists.
2009 Jul 15
3-[(5-Methyl-furan-2-yl)methyl-ene]-1,5-dioxaspiro-[5.5]undecane-2,4-dione.
2009 Jul 29
Synthetic mRNA splicing modulator compounds with in vivo antitumor activity.
2009 Nov 26
2-(2-Nitro-phen-yl)-1,3-dioxan-5-ol.
2009 Oct 28
5-(2-Fluoro-benzyl-idene)-2,2-dimethyl-1,3-dioxane-4,6-dione.
2009 Sep 30
(Z)-3-(3-Phenyl-allyl-idene)-1,5-dioxa-spiro-[5.5]undecane-2,4-dione.
2009 Sep 30
3,9-Di-1-naphthyl-2,4,8,10-tetra-oxa-spiro-[5.5]undeca-ne.
2010 Apr 28
5-(4-Hy-droxy-benzyl-idene)-2,2-dimethyl-1,3-dioxane-4,6-dione.
2010 Aug 18
5-(4-Fluoro-benzyl-idene)-2,2-dimethyl-1,3-dioxane-4,6-dione.
2010 Aug 21
(E)-1-[(1,3-Dioxan-4-yl)meth-yl]-2-(nitro-methyl-idene)imidazolidine.
2010 Aug 21
Product study of the OH radical and Cl atom initiated oxidation of 1,3-dioxane.
2010 Dec 17
3,9-Bis(2-chloro-phen-yl)-2,4,8,10-tetra-oxaspiro-[5.5]undeca-ne.
2010 Jan 23
2-(2-Naphth-yl)-1,3-dioxane.
2010 Jan 30
3,9-Bis(2,4-dichloro-phen-yl)-2,4,8,10-tetra-oxaspiro-[5.5]undeca-ne.
2010 Jun 30
Bifunctional hydrogen bonds in monohydrated cycloether complexes.
2010 Mar 4
Xyloccensin e.
2010 May 15
3,9-Di-tert-butyl-2,4,8,10-tetra-oxaspiro-[5.5]undeca-ne.
2010 Nov 30
Stereoselective α,α'-annelation reactions of 1,3-dioxan-5-ones.
2010 Nov 5
3-(4-Meth-oxy-benzyl-idene)-1,5-dioxa-spiro-[5.5]undecane-2,4-dione.
2010 Oct 20
3,3,9,9-Tetra-phenyl-2,4,8,10-tetra-oxa-spiro-[5.5]undeca-ne.
2010 Oct 31
Synthesis and characterization of novel indole derivatives reveal improved therapeutic agents for treatment of ischemia/reperfusion (I/R) injury.
2010 Sep 23
Name Type Language
1,3-DIOXANE
HSDB  
Systematic Name English
1,3-PROPANEDIOL FORMAL
Common Name English
1,3-DIOXANE [HSDB]
Common Name English
M-DIOXIN, DIHYDRO-
Systematic Name English
TRIMETHYLENE GLYCOL METHYLENE ETHER
Common Name English
1,3-DIOXACYCLOHEXANE
Systematic Name English
M-DIOXANE
Systematic Name English
NSC-139436
Code English
Code System Code Type Description
FDA UNII
B2C8M17I09
Created by admin on Fri Dec 15 17:12:47 GMT 2023 , Edited by admin on Fri Dec 15 17:12:47 GMT 2023
PRIMARY
CHEBI
46924
Created by admin on Fri Dec 15 17:12:47 GMT 2023 , Edited by admin on Fri Dec 15 17:12:47 GMT 2023
PRIMARY
NSC
139436
Created by admin on Fri Dec 15 17:12:47 GMT 2023 , Edited by admin on Fri Dec 15 17:12:47 GMT 2023
PRIMARY
EPA CompTox
DTXSID3025174
Created by admin on Fri Dec 15 17:12:47 GMT 2023 , Edited by admin on Fri Dec 15 17:12:47 GMT 2023
PRIMARY
ECHA (EC/EINECS)
208-005-1
Created by admin on Fri Dec 15 17:12:47 GMT 2023 , Edited by admin on Fri Dec 15 17:12:47 GMT 2023
PRIMARY
PUBCHEM
10450
Created by admin on Fri Dec 15 17:12:47 GMT 2023 , Edited by admin on Fri Dec 15 17:12:47 GMT 2023
PRIMARY
CAS
505-22-6
Created by admin on Fri Dec 15 17:12:47 GMT 2023 , Edited by admin on Fri Dec 15 17:12:47 GMT 2023
PRIMARY
HSDB
4263
Created by admin on Fri Dec 15 17:12:47 GMT 2023 , Edited by admin on Fri Dec 15 17:12:47 GMT 2023
PRIMARY
WIKIPEDIA
1,3-Dioxane
Created by admin on Fri Dec 15 17:12:47 GMT 2023 , Edited by admin on Fri Dec 15 17:12:47 GMT 2023
PRIMARY