1,3-DIOXANE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H8O2
Molecular Weight	88.1051
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C1COCOC1

InChI

InChIKey=VDFVNEFVBPFDSB-UHFFFAOYSA-N

InChI=1S/C4H8O2/c1-2-5-4-6-3-1/h1-4H2

HIDE SMILES / InChI

Molecular Formula	C4H8O2
Molecular Weight	88.1051
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Product study of the OH radical and Cl atom initiated oxidation of 1,3-dioxane.	2010-12-17	20949582
3,9-Di-tert-butyl-2,4,8,10-tetra-oxaspiro-[5.5]undeca-ne.	2010-11-30	21589636
Stereoselective α,α'-annelation reactions of 1,3-dioxan-5-ones.	2010-11-05	20936869
3,3,9,9-Tetra-phenyl-2,4,8,10-tetra-oxa-spiro-[5.5]undeca-ne.	2010-10-31	21589189
3-(4-Meth-oxy-benzyl-idene)-1,5-dioxa-spiro-[5.5]undecane-2,4-dione.	2010-10-20	21589023
Synthesis and characterization of novel indole derivatives reveal improved therapeutic agents for treatment of ischemia/reperfusion (I/R) injury.	2010-09-23	20731361
5-(4-Fluoro-benzyl-idene)-2,2-dimethyl-1,3-dioxane-4,6-dione.	2010-08-21	21588707
(E)-1-[(1,3-Dioxan-4-yl)meth-yl]-2-(nitro-methyl-idene)imidazolidine.	2010-08-21	21588701
5-(4-Hy-droxy-benzyl-idene)-2,2-dimethyl-1,3-dioxane-4,6-dione.	2010-08-18	21588666
3,9-Bis(2,4-dichloro-phen-yl)-2,4,8,10-tetra-oxaspiro-[5.5]undeca-ne.	2010-06-30	21588061
Xyloccensin e.	2010-05-15	21579436
3,9-Di-1-naphthyl-2,4,8,10-tetra-oxa-spiro-[5.5]undeca-ne.	2010-04-28	21579228
Bifunctional hydrogen bonds in monohydrated cycloether complexes.	2010-03-04	20136161
2-(2-Naphth-yl)-1,3-dioxane.	2010-01-30	21579883
3,9-Bis(2-chloro-phen-yl)-2,4,8,10-tetra-oxaspiro-[5.5]undeca-ne.	2010-01-23	21579841
Synthetic mRNA splicing modulator compounds with in vivo antitumor activity.	2009-11-26	19877647
2-(2-Nitro-phen-yl)-1,3-dioxan-5-ol.	2009-10-28	21578441
5-(2-Fluoro-benzyl-idene)-2,2-dimethyl-1,3-dioxane-4,6-dione.	2009-09-30	21578023
(Z)-3-(3-Phenyl-allyl-idene)-1,5-dioxa-spiro-[5.5]undecane-2,4-dione.	2009-09-30	21578022
3-[(5-Methyl-furan-2-yl)methyl-ene]-1,5-dioxaspiro-[5.5]undecane-2,4-dione.	2009-07-29	21583701
3-(2-Furylmethyl-ene)-1,5-dioxaspiro-[5.5]undecane-2,4-dione.	2009-07-15	21583569
Synthesis of uracil nucleotide analogs with a modified, acyclic ribose moiety as P2Y(2) receptor antagonists.	2009-07-15	19523835
Biodegradation of 1,4-dioxane and transformation of related cyclic compounds by a newly isolated Mycobacterium sp. PH-06.	2009-07	19085063
7,14-Bis(4-bromo-phen-yl)-2,11,11-trimethyl-1,4,10,12-tetra-oxa-dispiro-[4.2.5.2]penta-decane-9,13-dione.	2009-04-30	21583954
7,14-Bis(4-methoxy-phen-yl)-11,11-dimethyl-1,4,10,12-tetra-oxa-dispiro-[4.2.5.2]penta-decane-9,13-dione.	2009-04-18	21583891
2,3:4,6-Di-O-isopropylidene-alpha-L-sorbofuranose and 2,3-O-isopropylidene-alpha-L-sorbofuranose.	2009-04	19346611
2,2-Dimethyl-5-triphenyl-methyl-1,3-dioxane.	2009-01-14	21581913
Reactivity of 13,13-dibromo-2,4,9,11-tetraoxadispiro[5.0.5.1]tridecane toward organolithiums: remarkable resistance to the DMS rearrangement.	2008-08-01	18578498
5,5-Bis(hydroxy-meth-yl)-2-phenyl-1,3-dioxane.	2008-07-19	21203241
Synthesis of polynucleotide analogs containing a polyvinyl alcohol backbone.	2008-03-26	18463571
Sugar derived hexacoordinated phosphates: chiral anionic auxiliaries with general asymmetric efficiency.	2008-03	17614326
New 1,3-dioxolane and 1,3-dioxane derivatives as effective modulators to overcome multidrug resistance.	2007-03-15	17276076
Oxygenation vs iodonio substitution during the reactions of alkenyl-silanes with iodosylbenzene: participation of the internal oxy group.	2007-03-12	17347718
Ambient-pressure organic superconductors kappa-(DMEDO-TSeF)2[Au(CN)4](solv.): Tc tuning by modification of the solvent of crystallization.	2007	17610218
Photoreactions in the gas-phase complexes of Mg(*+)-dioxanes.	2006-04-06	16571042
Relationships between the structure of dexoxadrol and etoxadrol analogues and their NMDA receptor affinity.	2006	16719812
Hybrid density functional theory study of fragment ions generated during mass spectrometry of 1,3-dioxane derivatives.	2006	16715477
Conformational pathways of saturated six-membered rings. A static and dynamical density functional study.	2005-09-15	16834195
Modular synthesis and preliminary biological evaluation of stereochemically diverse 1,3-dioxanes.	2004-09	15380188
Modeling deoxyribose radicals by neutralization-reionization mass spectrometry. Part 1. Preparation, dissociations, and energetics of 2-hydroxyoxolan-2-yl radical, neutral isomers, and cations.	2004-07	15234364
Design and synthesis of new macrocyclic cyclophanes using 1,3-dioxane units as bridges: a molecular "rocking chair".	2004-02-20	14961688
Synthesis and NMDA-receptor affinity of ring and side chain homologous dexoxadrol derivatives.	2004-02	14981662
Exclusive formation of alpha-methyleneoxetanes in ketene-alkene cycloadditions. Evidence for intervention of both an alpha-methyleneoxetane and the subsequent 1,4-zwitterion.	2003-11-26	14624592
Palladium-catalyzed Heck reaction on 1-alkoxy-1,3-dienes: a regioselective gamma-arylation of alpha,beta-unsaturated carbonyl compounds.	2003-10-16	14535717
Structural biasing elements for in-cell histone deacetylase paralog selectivity.	2003-05-14	12733869
Synthesis of a novel series of tricyclic indan derivatives as melatonin receptor agonists.	2002-09-12	12213063
Effect of geminal substitution on the strain energy of dioxiranes. Origin of the low ring strain of dimethyldioxirane.	2002-05-31	12027708
Synthesis and biological activity of 1-phenylsulfonyl-4-phenylsulfonylaminopyrrolidine derivatives as thromboxane a(2) receptor antagonists.	2002-05	11886803
Can the stereochemical outcome of glycosylation reactions be controlled by the conformational preferences of the glycosyl donor?	2002-04-17	11950473
Diastereoselective synthesis of protected syn 1,3-diols: preparation of the C16-C24 portion of Dolabelides.	2002-02-07	11820894

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:42:11 GMT 2025` Edited by `admin` on `Mon Mar 31 18:42:11 GMT 2025`
Record UNII	B2C8M17I09
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1,3-DIOXANE

Systematic Name

English

NSC-139436

Preferred Name

English

1,3-PROPANEDIOL FORMAL

Common Name

English

1,3-DIOXANE [HSDB]

Common Name

English

M-DIOXIN, DIHYDRO-

Systematic Name

English

TRIMETHYLENE GLYCOL METHYLENE ETHER

Common Name

English

1,3-DIOXACYCLOHEXANE

Systematic Name

English

M-DIOXANE

Systematic Name

English

Code System Code Type Description

FDA UNII

B2C8M17I09