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Details

Stereochemistry ABSOLUTE
Molecular Formula C6H12O5
Molecular Weight 164.1565
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1,4-SORBITAN

SMILES

[H][C@@]1(OC[C@H](O)[C@H]1O)[C@H](O)CO

InChI

InChIKey=JNYAEWCLZODPBN-JGWLITMVSA-N
InChI=1S/C6H12O5/c7-1-3(8)6-5(10)4(9)2-11-6/h3-10H,1-2H2/t3-,4+,5-,6-/m1/s1

HIDE SMILES / InChI
1,4-Sorbitan is a sorbitol anhydration product. 1,4-Sorbitan is a precursor to environmentally benign surfactants. It is a component of Sorbitol-Sorbitan mixtures used as soft gel plasticizers. They enhance the soft gelatin capsule finish gloss for a premium appearance, help to prevent leakage, provide consistent pharmaceutical quality, and extend shelf life by maintaining a proper moisture balance within the capsule shell.

Approval Year

PubMed

PubMed

TitleDatePubMed
Sorbitan monopalmitate-based proniosomes for transdermal delivery of chlorpheniramine maleate.
2005 Mar-Apr
Formulation and evaluation of a vitamin C multiple emulsion.
2006
Optimization of lipase-catalyzed synthesis of sorbitan acrylate using response surface methodology.
2007 Apr
Phase transition water-in-oil microemulsions as ocular drug delivery systems: in vitro and in vivo evaluation.
2007 Jan 2
The use of solvent relaxation technique to investigate headgroup hydration and protein binding of simple and mixed phosphatidylcholine/surfactant bilayer membranes.
2007 May
Some considerations about the hydrophilic-lipophilic balance system.
2008 May 22
Efficacy of niosomal formulation of diallyl sulfide against experimental candidiasis in Swiss albino mice.
2009 Oct
Between the devil and the deep blue sea: dispersants in the gulf of Mexico.
2010 Aug
Patents
Name Type Language
1,4-SORBITAN
USP-RS  
Common Name English
1,4-ANHYDRO-D-GLUCITOL
Common Name English
1,4-ANHYDROSORBITOL
Common Name English
1,4-SORBITAN [USP-RS]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C83486
Created by admin on Fri Dec 15 16:06:18 GMT 2023 , Edited by admin on Fri Dec 15 16:06:18 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C83509
Created by admin on Fri Dec 15 16:06:18 GMT 2023 , Edited by admin on Fri Dec 15 16:06:18 GMT 2023
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CAS
27299-12-3
Created by admin on Fri Dec 15 16:06:18 GMT 2023 , Edited by admin on Fri Dec 15 16:06:18 GMT 2023
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DAILYMED
AV0YTZ4E6J
Created by admin on Fri Dec 15 16:06:18 GMT 2023 , Edited by admin on Fri Dec 15 16:06:18 GMT 2023
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EPA CompTox
DTXSID50893383
Created by admin on Fri Dec 15 16:06:18 GMT 2023 , Edited by admin on Fri Dec 15 16:06:18 GMT 2023
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ECHA (EC/EINECS)
248-391-9
Created by admin on Fri Dec 15 16:06:18 GMT 2023 , Edited by admin on Fri Dec 15 16:06:18 GMT 2023
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PUBCHEM
10953859
Created by admin on Fri Dec 15 16:06:18 GMT 2023 , Edited by admin on Fri Dec 15 16:06:18 GMT 2023
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FDA UNII
AV0YTZ4E6J
Created by admin on Fri Dec 15 16:06:18 GMT 2023 , Edited by admin on Fri Dec 15 16:06:18 GMT 2023
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RXCUI
1307571
Created by admin on Fri Dec 15 16:06:18 GMT 2023 , Edited by admin on Fri Dec 15 16:06:18 GMT 2023
PRIMARY RxNorm
SMS_ID
100000087532
Created by admin on Fri Dec 15 16:06:18 GMT 2023 , Edited by admin on Fri Dec 15 16:06:18 GMT 2023
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RS_ITEM_NUM
1616008
Created by admin on Fri Dec 15 16:06:18 GMT 2023 , Edited by admin on Fri Dec 15 16:06:18 GMT 2023
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EVMPD
SUB21060
Created by admin on Fri Dec 15 16:06:18 GMT 2023 , Edited by admin on Fri Dec 15 16:06:18 GMT 2023
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