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Details

Stereochemistry ABSOLUTE
Molecular Formula C6H12O5
Molecular Weight 164.1565
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1,4-SORBITAN

SMILES

OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O

InChI

InChIKey=JNYAEWCLZODPBN-JGWLITMVSA-N
InChI=1S/C6H12O5/c7-1-3(8)6-5(10)4(9)2-11-6/h3-10H,1-2H2/t3-,4+,5-,6-/m1/s1

HIDE SMILES / InChI

Description

1,4-Sorbitan is a sorbitol anhydration product. 1,4-Sorbitan is a precursor to environmentally benign surfactants. It is a component of Sorbitol-Sorbitan mixtures used as soft gel plasticizers. They enhance the soft gelatin capsule finish gloss for a premium appearance, help to prevent leakage, provide consistent pharmaceutical quality, and extend shelf life by maintaining a proper moisture balance within the capsule shell.

Originator

Approval Year

1986
107
PubMed

PubMed

TitleDatePubMed
Optimization of lipase-catalyzed synthesis of sorbitan acrylate using response surface methodology.
2007 Apr
Bioremediation of diesel fuel contaminated soil: effect of non ionic surfactants and selected bacteria addition.
2007 Sep
Dermal delivery of selected hydrophilic drugs from elastic liposomes: effect of phospholipid formulation and surfactants.
2007 Sep
Selection of surfactants for enhancing diesel hydrocarbons-contaminated media bioremediation.
2008 Apr 15
Allergens in corticosteroid vehicles.
2008 Jan-Feb
Some considerations about the hydrophilic-lipophilic balance system.
2008 May 22
Comparative study on the effects of some polyoxyethylene alkyl ether and sorbitan fatty acid ester surfactants on the performance of transdermal carvedilol proniosomal gel using experimental design.
2010 Dec
Niosome as a drug carrier for topical delivery of N-acetyl glucosamine.
2010 Jul
Patents

Patents

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JP2000103701A
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JP2000109707A
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JP2000116325A
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JP2000119687A
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JP2000119688A
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JP2000129251A
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JP2000159660A
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JP2000169583A
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JP2000203979A
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JP2000212485A
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JP2000264831A
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JP2000313834A
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JP2000351726A
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JP2002322495A
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JP2002327371A
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JP2003049193A
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JP2004141126A
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JP2004168851A
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JP2004168852A
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JP2004315713A
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JP2005002078A
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JP2005008599A
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JP2005013117A
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JP2005060683A
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JP2005521552A
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JP2005523776A
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JP2006111542A
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JP2006183016A
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JP2006191853A
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JP2006503941A
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JP2007124937A
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JP2007153770A
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JP2008042216A
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JP2008063476A
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JP2008143996A
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JP2008546165A
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JP2009209220A
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JP2010536837A
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Name Type Language
1,4-ANHYDRO-D-GLUCITOL
Preferred Name English
1,4-SORBITAN
USP-RS  
Common Name English
1,4-ANHYDROSORBITOL
Common Name English
1,4-SORBITAN [USP-RS]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C83486
Created by admin on Mon Mar 31 18:19:09 GMT 2025 , Edited by admin on Mon Mar 31 18:19:09 GMT 2025
Code System Code Type Description
NCI_THESAURUS
C83509
Created by admin on Mon Mar 31 18:19:09 GMT 2025 , Edited by admin on Mon Mar 31 18:19:09 GMT 2025
PRIMARY
CAS
27299-12-3
Created by admin on Mon Mar 31 18:19:09 GMT 2025 , Edited by admin on Mon Mar 31 18:19:09 GMT 2025
PRIMARY
DAILYMED
AV0YTZ4E6J
Created by admin on Mon Mar 31 18:19:09 GMT 2025 , Edited by admin on Mon Mar 31 18:19:09 GMT 2025
PRIMARY
EPA CompTox
DTXSID50893383
Created by admin on Mon Mar 31 18:19:09 GMT 2025 , Edited by admin on Mon Mar 31 18:19:09 GMT 2025
PRIMARY
ECHA (EC/EINECS)
248-391-9
Created by admin on Mon Mar 31 18:19:09 GMT 2025 , Edited by admin on Mon Mar 31 18:19:09 GMT 2025
PRIMARY
PUBCHEM
10953859
Created by admin on Mon Mar 31 18:19:09 GMT 2025 , Edited by admin on Mon Mar 31 18:19:09 GMT 2025
PRIMARY
FDA UNII
AV0YTZ4E6J
Created by admin on Mon Mar 31 18:19:09 GMT 2025 , Edited by admin on Mon Mar 31 18:19:09 GMT 2025
PRIMARY
RXCUI
1307571
Created by admin on Mon Mar 31 18:19:09 GMT 2025 , Edited by admin on Mon Mar 31 18:19:09 GMT 2025
PRIMARY RxNorm
SMS_ID
100000087532
Created by admin on Mon Mar 31 18:19:09 GMT 2025 , Edited by admin on Mon Mar 31 18:19:09 GMT 2025
PRIMARY
RS_ITEM_NUM
1616008
Created by admin on Mon Mar 31 18:19:09 GMT 2025 , Edited by admin on Mon Mar 31 18:19:09 GMT 2025
PRIMARY
EVMPD
SUB21060
Created by admin on Mon Mar 31 18:19:09 GMT 2025 , Edited by admin on Mon Mar 31 18:19:09 GMT 2025
PRIMARY
SUBSTANCE RECORD
Structure of 1,4-SORBITAN
NIH
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