Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C6H12O5 |
Molecular Weight | 164.1565 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]1(OC[C@H](O)[C@H]1O)[C@H](O)CO
InChI
InChIKey=JNYAEWCLZODPBN-JGWLITMVSA-N
InChI=1S/C6H12O5/c7-1-3(8)6-5(10)4(9)2-11-6/h3-10H,1-2H2/t3-,4+,5-,6-/m1/s1
1,4-Sorbitan is a sorbitol anhydration product. 1,4-Sorbitan is a precursor to environmentally benign surfactants. It is a component of Sorbitol-Sorbitan mixtures used as soft gel plasticizers. They enhance the soft gelatin capsule finish gloss for a premium appearance, help to prevent leakage, provide consistent pharmaceutical quality, and extend shelf life by maintaining a proper moisture balance within the capsule shell.
Originator
Approval Year
PubMed
Title | Date | PubMed |
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Sorbitan monopalmitate-based proniosomes for transdermal delivery of chlorpheniramine maleate. | 2005 Mar-Apr |
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Formulation and evaluation of a vitamin C multiple emulsion. | 2006 |
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Optimization of lipase-catalyzed synthesis of sorbitan acrylate using response surface methodology. | 2007 Apr |
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Phase transition water-in-oil microemulsions as ocular drug delivery systems: in vitro and in vivo evaluation. | 2007 Jan 2 |
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The use of solvent relaxation technique to investigate headgroup hydration and protein binding of simple and mixed phosphatidylcholine/surfactant bilayer membranes. | 2007 May |
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Some considerations about the hydrophilic-lipophilic balance system. | 2008 May 22 |
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Efficacy of niosomal formulation of diallyl sulfide against experimental candidiasis in Swiss albino mice. | 2009 Oct |
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Between the devil and the deep blue sea: dispersants in the gulf of Mexico. | 2010 Aug |
Patents
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Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C83486
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C83509
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27299-12-3
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AV0YTZ4E6J
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DTXSID50893383
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248-391-9
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10953859
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AV0YTZ4E6J
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1307571
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100000087532
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1616008
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SUB21060
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SUBSTANCE RECORD