CLOCINIZINE HYDROCHLORIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C26H27ClN2.2ClH
Molecular Weight	475.881
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.Cl.ClC1=CC=C(C=C1)C(N2CCN(C\C=C\C3=CC=CC=C3)CC2)C4=CC=CC=C4

InChI

InChIKey=YFQRGPYJACKPRU-WRQJSNHTSA-N

InChI=1S/C26H27ClN2.2ClH/c27-25-15-13-24(14-16-25)26(23-11-5-2-6-12-23)29-20-18-28(19-21-29)17-7-10-22-8-3-1-4-9-22;;/h1-16,26H,17-21H2;2*1H/b10-7+;;

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Description
Sources: https://www.vademecum.es/medicamento-senioral_ficha_3612

Clocinizine is an antihistamine derivative of diphenylmethylpiperazine. Clocinizine is a competitive and reversible H1 receptor antagonist. The drug is marketed in Spain under tradename Senioral in combination with phenylpropanolamine for temporary relief of nasal congestion in colds, rhinitis, and sinusitis.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Histamine H1 receptor 316 Target ID: CHEMBL231 Sources: https://www.drugs.com/international/clocinizine.html \| http://www.hmdb.ca/metabolites/HMDB0240242	Antagonist 2849

Name

Type

Language

CLIOCINIZINE HYDROCHLORIDE

Preferred Name

English

CLOCINIZINE HYDROCHLORIDE

Common Name

English

1-((4-CHLOROPHENYL)PHENYLMETHYL)-4-(3-PHENYL-2-PROPENYL)PIPERAZINE DIHYDROCHLORIDE

Systematic Name

English

CLOCINIZINE DIHYDROCHLORIDE

Common Name

English

Clocinizine hydrochloride [WHO-DD]

Common Name

English

PIPERAZINE, 1-((4-CHLOROPHENYL)PHENYLMETHYL)-4-(3-PHENYL-2-PROPEN-1-YL)-, HYDROCHLORIDE (1:2)

Systematic Name

English

CLOCINIZINE HYDROCHLORIDE [MART.]

Common Name

English

1-CINNAMYL-4-(4-CHLOROBENZHYDRYL)PIPERAZINE DIHYDROCHLORIDE

Systematic Name

English

CLOCINIZINE HCL

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29578