AZINTAMIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H14ClN3OS
Molecular Weight	259.756
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of AZINTAMIDE

Structure Search

SMILES

CCN(CC)C(=O)CSC1=NN=C(Cl)C=C1

InChI

InChIKey=SSLKKMZJCJBOML-UHFFFAOYSA-N

InChI=1S/C10H14ClN3OS/c1-3-14(4-2)10(15)7-16-9-6-5-8(11)12-13-9/h5-6H,3-4,7H2,1-2H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6628788 | https://www.ncbi.nlm.nih.gov/pubmed/21600084

Azintamide was initially studied as a therapeutic agent in psoriasis vulgaris. Then was shown, the drug was effective and safe in the treatment of patients with dyspepsia symptoms by the modulation of visceral sensitivity and/or gastrointestinal motility.

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
dyspepsia symptoms 1 Sources: https://www.ncbi.nlm.nih.gov/pubmed/19080231	Primary		Not Provided 504	Unknown Approved Use Unknown

PubMed

PubMed

Title	Date	PubMed
[Azintamid as a therapeutic agent in psoriasis vulgaris - a therapeutic study].	1983	6628788
[Efficacy and safety of compound azintamide on dyspepsia symptoms in a multicentre self-controlled trial].	2008 Nov	19080231

Sample Use Guides

In Vivo Use Guide

Two tablets of compound azintamide were administered orally following a meal, tid for 2 weeks

Route of Administration: Oral

Name

Type

Language

AZINTAMIDE

Official Name

English

2-((6-CHLORO-3-PYRIDAZINYL)THIO)-N,N-DIETHYLACETAMIDE

Systematic Name

English

NSC-291837

Code

English

Azintamide [WHO-DD]

Common Name

English

ST 9067

Code

English

AZINTAMIDE [MART.]

Common Name

English

AZINTAMIDE [MI]

Common Name

English

AZINTHIAMIDE

Common Name

English

COLERIN

Brand Name

English

azintamide [INN]

Common Name

English

ST-9067

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C66913

Created by admin on Sat Dec 16 16:31:40 GMT 2023 , Edited by admin on Sat Dec 16 16:31:40 GMT 2023

Code System Code Type Description

PUBCHEM

71105

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PRIMARY

FDA UNII

ACZ6L64B41

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DRUG BANK

DB13992

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NSC

291837

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SMS_ID

100000086085

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ECHA (EC/EINECS)

217-384-2

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EPA CompTox

DTXSID50171370

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DRUG CENTRAL

275

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EVMPD

SUB05658MIG

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INN

2063

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MERCK INDEX

m1019

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Merck Index

NCI_THESAURUS

C74232

Created by admin on Sat Dec 16 16:31:40 GMT 2023 , Edited by admin on Sat Dec 16 16:31:40 GMT 2023

PRIMARY

CAS

1830-32-6

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PRIMARY

ChEMBL

CHEMBL2104678

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RXCUI

402580

Created by admin on Sat Dec 16 16:31:40 GMT 2023 , Edited by admin on Sat Dec 16 16:31:40 GMT 2023

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RxNorm

ACTIVE MOIETY


					ACZ6L64B41