IRTEMAZOLE

Details

Stereochemistry	RACEMIC
Molecular Formula	C18H16N4
Molecular Weight	288.3464
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=NC2=C(N1)C=C(C=C2)C(N3C=CN=C3)C4=CC=CC=C4

InChI

InChIKey=DCGOMTSIZLGUOK-UHFFFAOYSA-N

InChI=1S/C18H16N4/c1-13-20-16-8-7-15(11-17(16)21-13)18(22-10-9-19-12-22)14-5-3-2-4-6-14/h2-12,18H,1H3,(H,20,21)

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Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2615290 | https://www.ncbi.nlm.nih.gov/pubmed/2586012

IRTEMAZOLE is a uricosuric agent exhibiting a rapid uricosuric effect in normouricemic as well as in hyperuricemic persons.

Originator

Approval Year

PubMed

Title	Date	PubMed
A new uricosuric substance 5-[(1H-imidazol-1-yl)phenylmethyl]-2-methyl-1H-benzimidazole (C18H16N4).	1989 Jun 15	2770180
Rapid onset of uricosuria after oral administration of irtemazole, an uricosuric substance.	1989 Oct 17	2586012

Patents

Name

Type

Language

IRTEMAZOLE

Official Name

English

IRTEMAZOLE [USAN]

Common Name

English

1H-BENZIMIDAZOLE, 5-(1H-IMIDAZOL-1-YLPHENYLMETHYL)-2-METHYL-

Systematic Name

English

1H-BENZIMIDAZOLE, 5-(1H-IMIDAZOL-1-YLPHENYLMETHYL)-2-METHYL-, (±)-

Common Name

English

(±)-5-(.ALPHA.-IMIDAZOL-1-YLBENZYL)-2-METHYLBENZIMIDAZOLE

Common Name

English

1H-BENZIMIDAZOLE, 6-(1H-IMIDAZOL-1-YLPHENYLMETHYL)-2-METHYL-

Systematic Name

English

R-60844

Code

English

irtemazole [INN]

Common Name

English

R60844

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C921