U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

PubMed

PubMed

TitleDatePubMed
Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently.
2015-04-01
Correlation of gene expression and contaminant concentrations in wild largescale suckers: a field-based study.
2014-06-15
Regulation of hepatic drug transporter activity and expression by organochlorine pesticides.
2014-03
Hypothyroidism and pesticide use among male private pesticide applicators in the agricultural health study.
2013-10
Characteristic molecular signature for early detection and prediction of persistent organic pollutants in rat liver.
2012-12-04
Differential effects of a complex organochlorine mixture on the proliferation of breast cancer cell lines.
2011-04
Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays.
2011-02-27
Fetal exposure to chlordane and permethrin mixtures in relation to inflammatory cytokines and birth outcomes.
2011-02-15
Regulation and dysregulation of vitellogenin mRNA accumulation in daphnids (Daphnia magna).
2011-01-25
Inhibition of connexin 43 gap junction channels by the endocrine disruptor ioxynil.
2010-08-15
Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo.
2010-08
Pesticide use and thyroid disease among women in the Agricultural Health Study.
2010-02-15
The B[a]P-increased intercellular communication via translocation of connexin-43 into gap junctions reduces apoptosis.
2010-01-15
Pesticide use and adult-onset asthma among male farmers in the Agricultural Health Study.
2009-12
Incident diabetes and pesticide exposure among licensed pesticide applicators: Agricultural Health Study, 1993-2003.
2008-05-15
Occupational exposure to organochlorine insecticides and cancer incidence in the Agricultural Health Study.
2007-02-01
Differential activation of wild-type estrogen receptor alpha and C-terminal deletion mutants by estrogens, antiestrogens and xenoestrogens in breast cancer cells.
2007-01
Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line.
2006-11-10
Activation of alpha- and beta-estrogen receptors by persistent pesticides in reporter cell lines.
2006-08-15
Estrogen-related receptors as emerging targets in cancer and metabolic disorders.
2006
CAR and PXR: xenosensors of endocrine disrupters?
2005-08-15
Positive and negative transcriptional regulation of aromatase expression in human breast cancer tissue.
2005-05
Activation of retinoic acid receptor-dependent transcription by organochlorine pesticides.
2005-01-01
A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides.
2004-12-15
Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells.
2004-04
Carcinogen-metabolizing enzymes and insecticides.
2004
PXR-dependent induction of human CYP3A4 gene expression by organochlorine pesticides.
2002-11-15
Modulation of prolactin expression by xenoestrogens.
2002-04
Modulation of aromatase expression in human breast tissue.
2001-12
Role of PKC and MAP kinase in EGF- and TPA-induced connexin43 phosphorylation and inhibition of gap junction intercellular communication in rat liver epithelial cells.
2001-09
Two organochlorine pesticides, toxaphene and chlordane, are antagonists for estrogen-related receptor alpha-1 orphan receptor.
1999-09-15
Effect of the chlorinated hydrocarbons heptachlor, chlordane, and toxaphene on retinoblastoma tumor suppressor in human lymphocytes.
1999-01-11
The human acrosome reaction is highly sensitive to inhibition by cyclodiene insecticides.
1998-02-12
Quantitative relationship between transforming growth factor-alpha and hepatic focal phenotype and progression in female mouse liver.
1997-05-01
In vitro synergistic interaction of alligator and human estrogen receptors with combinations of environmental chemicals.
1997-04
In vitro and in vivo induction of heat shock (stress) protein (Hsp) gene expression by selected pesticides.
1996-08-01
Comparison of the activity of topically applied pesticides and the herbicide 2,4-D in two short-term in vivo assays of genotoxicity in the mouse.
1990-11
Morphologic and cytochemical properties of mouse liver neoplasms induced by diethylnitrosamine and promoted by 4,4'-dichlorodiphenyltrichloroethane, chlordane, or heptachlor.
1985
Effect of parathion, malathion, endosulfan and chlordane on porphyrin accumulation and ALA-synthetase in chick embryo liver.
1982
Patents

Patents

Name Type Language
CHLORDANE
HSDB   MART.   MI  
Common Name English
CORODANE
Preferred Name English
INTOX
Brand Name English
SYNKLOR
Brand Name English
CHLORDAN
Common Name English
CHLORDANE [HSDB]
Common Name English
CHLORDANE [MI]
Common Name English
TOXICHLOR
Brand Name English
1,2,4,5,6,7,8,8-OCTACHLORO-2,3,3A,4,7,7A-HEXAHYDRO-4,7-METHANO-1H-INDENE
Common Name English
DOWCHLOR
Brand Name English
M-140
Code English
CHLORDANE [IARC]
Common Name English
NSC-8931
Code English
CHLORDANE [MART.]
Common Name English
ORTHO-KLOR
Brand Name English
OCTACHLOR
Brand Name English
NIRAN
Brand Name English
COMPOUND K
Common Name English
TAT CHLOR 4
Brand Name English
ENT-9932
Code English
CHLORINDAN
Common Name English
HCS-3260
Code English
OKTATERR
Brand Name English
CD-68
Code English
VELSICOL 1068
Brand Name English
1,2,4,5,6,7,8,8-OCTACHLORO-2,3,3A,4,7,7A-HEXAHYDRO-4,7-METHANOINDENE
Common Name English
TECHNICAL CHLORDANE
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 58201
Created by admin on Mon Mar 31 18:35:46 GMT 2025 , Edited by admin on Mon Mar 31 18:35:46 GMT 2025
IARC Chlordane
NCI_THESAURUS C737
Created by admin on Mon Mar 31 18:35:46 GMT 2025 , Edited by admin on Mon Mar 31 18:35:46 GMT 2025
Code System Code Type Description
FDA UNII
A9RLM212CY
Created by admin on Mon Mar 31 18:35:46 GMT 2025 , Edited by admin on Mon Mar 31 18:35:46 GMT 2025
PRIMARY
EVMPD
SUB33050
Created by admin on Mon Mar 31 18:35:46 GMT 2025 , Edited by admin on Mon Mar 31 18:35:46 GMT 2025
PRIMARY
ECHA (EC/EINECS)
200-349-0
Created by admin on Mon Mar 31 18:35:46 GMT 2025 , Edited by admin on Mon Mar 31 18:35:46 GMT 2025
PRIMARY
MERCK INDEX
m3353
Created by admin on Mon Mar 31 18:35:46 GMT 2025 , Edited by admin on Mon Mar 31 18:35:46 GMT 2025
PRIMARY Merck Index
CHEBI
34623
Created by admin on Mon Mar 31 18:35:46 GMT 2025 , Edited by admin on Mon Mar 31 18:35:46 GMT 2025
PRIMARY
NSC
8931
Created by admin on Mon Mar 31 18:35:46 GMT 2025 , Edited by admin on Mon Mar 31 18:35:46 GMT 2025
PRIMARY
WIKIPEDIA
CHLORDANE
Created by admin on Mon Mar 31 18:35:46 GMT 2025 , Edited by admin on Mon Mar 31 18:35:46 GMT 2025
PRIMARY
ALANWOOD
chlordane
Created by admin on Mon Mar 31 18:35:46 GMT 2025 , Edited by admin on Mon Mar 31 18:35:46 GMT 2025
PRIMARY
CAS
12789-03-6
Created by admin on Mon Mar 31 18:35:46 GMT 2025 , Edited by admin on Mon Mar 31 18:35:46 GMT 2025
NO STRUCTURE GIVEN
SMS_ID
100000125925
Created by admin on Mon Mar 31 18:35:46 GMT 2025 , Edited by admin on Mon Mar 31 18:35:46 GMT 2025
PRIMARY
HSDB
802
Created by admin on Mon Mar 31 18:35:46 GMT 2025 , Edited by admin on Mon Mar 31 18:35:46 GMT 2025
PRIMARY
CAS
57-74-9
Created by admin on Mon Mar 31 18:35:46 GMT 2025 , Edited by admin on Mon Mar 31 18:35:46 GMT 2025
PRIMARY
EPA CompTox
DTXSID7020267
Created by admin on Mon Mar 31 18:35:46 GMT 2025 , Edited by admin on Mon Mar 31 18:35:46 GMT 2025
PRIMARY
NCI_THESAURUS
C29814
Created by admin on Mon Mar 31 18:35:46 GMT 2025 , Edited by admin on Mon Mar 31 18:35:46 GMT 2025
PRIMARY
MESH
D002706
Created by admin on Mon Mar 31 18:35:46 GMT 2025 , Edited by admin on Mon Mar 31 18:35:46 GMT 2025
PRIMARY
All of the following components must be present:
Definition References