U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

PubMed

PubMed

TitleDatePubMed
Effect of parathion, malathion, endosulfan and chlordane on porphyrin accumulation and ALA-synthetase in chick embryo liver.
1982
Morphologic and cytochemical properties of mouse liver neoplasms induced by diethylnitrosamine and promoted by 4,4'-dichlorodiphenyltrichloroethane, chlordane, or heptachlor.
1985
Comparison of the activity of topically applied pesticides and the herbicide 2,4-D in two short-term in vivo assays of genotoxicity in the mouse.
1990 Nov
In vitro and in vivo induction of heat shock (stress) protein (Hsp) gene expression by selected pesticides.
1996 Aug 1
In vitro synergistic interaction of alligator and human estrogen receptors with combinations of environmental chemicals.
1997 Apr
Quantitative relationship between transforming growth factor-alpha and hepatic focal phenotype and progression in female mouse liver.
1997 May-Jun
The human acrosome reaction is highly sensitive to inhibition by cyclodiene insecticides.
1997 Nov-Dec
Effect of the chlorinated hydrocarbons heptachlor, chlordane, and toxaphene on retinoblastoma tumor suppressor in human lymphocytes.
1999 Jan 11
Two organochlorine pesticides, toxaphene and chlordane, are antagonists for estrogen-related receptor alpha-1 orphan receptor.
1999 Sep 15
Modulation of aromatase expression in human breast tissue.
2001 Dec
Role of PKC and MAP kinase in EGF- and TPA-induced connexin43 phosphorylation and inhibition of gap junction intercellular communication in rat liver epithelial cells.
2001 Sep
Modulation of prolactin expression by xenoestrogens.
2002 Apr
PXR-dependent induction of human CYP3A4 gene expression by organochlorine pesticides.
2002 Nov 15
Carcinogen-metabolizing enzymes and insecticides.
2004
Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells.
2004 Apr
A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides.
2004 Dec 15
CAR and PXR: xenosensors of endocrine disrupters?
2005 Aug 15
Activation of retinoic acid receptor-dependent transcription by organochlorine pesticides.
2005 Jan 1
Positive and negative transcriptional regulation of aromatase expression in human breast cancer tissue.
2005 May
Estrogen-related receptors as emerging targets in cancer and metabolic disorders.
2006
Activation of alpha- and beta-estrogen receptors by persistent pesticides in reporter cell lines.
2006 Aug 15
Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line.
2006 Nov 10
Occupational exposure to organochlorine insecticides and cancer incidence in the Agricultural Health Study.
2007 Feb 1
Differential activation of wild-type estrogen receptor alpha and C-terminal deletion mutants by estrogens, antiestrogens and xenoestrogens in breast cancer cells.
2007 Jan
Incident diabetes and pesticide exposure among licensed pesticide applicators: Agricultural Health Study, 1993-2003.
2008 May 15
Pesticide use and adult-onset asthma among male farmers in the Agricultural Health Study.
2009 Dec
Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo.
2010 Aug
Inhibition of connexin 43 gap junction channels by the endocrine disruptor ioxynil.
2010 Aug 15
Pesticide use and thyroid disease among women in the Agricultural Health Study.
2010 Feb 15
The B[a]P-increased intercellular communication via translocation of connexin-43 into gap junctions reduces apoptosis.
2010 Jan 15
Differential effects of a complex organochlorine mixture on the proliferation of breast cancer cell lines.
2011 Apr
Fetal exposure to chlordane and permethrin mixtures in relation to inflammatory cytokines and birth outcomes.
2011 Feb 15
Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays.
2011 Feb 27
Regulation and dysregulation of vitellogenin mRNA accumulation in daphnids (Daphnia magna).
2011 Jan 25
Characteristic molecular signature for early detection and prediction of persistent organic pollutants in rat liver.
2012 Dec 4
Hypothyroidism and pesticide use among male private pesticide applicators in the agricultural health study.
2013 Oct
Correlation of gene expression and contaminant concentrations in wild largescale suckers: a field-based study.
2014 Jun 15
Regulation of hepatic drug transporter activity and expression by organochlorine pesticides.
2014 Mar
Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently.
2015 Apr 1
Patents

Patents

Substance Class Mixture
Created
by admin
on Fri Dec 15 16:45:46 GMT 2023
Edited
by admin
on Fri Dec 15 16:45:46 GMT 2023
Record UNII
A9RLM212CY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CHLORDANE
HSDB   MART.   MI  
Common Name English
INTOX
Brand Name English
CORODANE
Brand Name English
SYNKLOR
Brand Name English
CHLORDAN
Common Name English
CHLORDANE [HSDB]
Common Name English
CHLORDANE [MI]
Common Name English
TOXICHLOR
Brand Name English
1,2,4,5,6,7,8,8-OCTACHLORO-2,3,3A,4,7,7A-HEXAHYDRO-4,7-METHANO-1H-INDENE
Common Name English
DOWCHLOR
Brand Name English
M-140
Code English
CHLORDANE [IARC]
Common Name English
NSC-8931
Code English
CHLORDANE [MART.]
Common Name English
ORTHO-KLOR
Brand Name English
OCTACHLOR
Brand Name English
NIRAN
Brand Name English
COMPOUND K
Common Name English
TAT CHLOR 4
Brand Name English
ENT-9932
Code English
CHLORINDAN
Common Name English
HCS-3260
Code English
OKTATERR
Brand Name English
CD-68
Code English
VELSICOL 1068
Brand Name English
1,2,4,5,6,7,8,8-OCTACHLORO-2,3,3A,4,7,7A-HEXAHYDRO-4,7-METHANOINDENE
Common Name English
TECHNICAL CHLORDANE
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 58201
Created by admin on Fri Dec 15 16:45:46 GMT 2023 , Edited by admin on Fri Dec 15 16:45:46 GMT 2023
IARC Chlordane
NCI_THESAURUS C737
Created by admin on Fri Dec 15 16:45:46 GMT 2023 , Edited by admin on Fri Dec 15 16:45:46 GMT 2023
Code System Code Type Description
FDA UNII
A9RLM212CY
Created by admin on Fri Dec 15 16:45:46 GMT 2023 , Edited by admin on Fri Dec 15 16:45:46 GMT 2023
PRIMARY
EVMPD
SUB33050
Created by admin on Fri Dec 15 16:45:46 GMT 2023 , Edited by admin on Fri Dec 15 16:45:46 GMT 2023
PRIMARY
ECHA (EC/EINECS)
200-349-0
Created by admin on Fri Dec 15 16:45:46 GMT 2023 , Edited by admin on Fri Dec 15 16:45:46 GMT 2023
PRIMARY
MERCK INDEX
m3353
Created by admin on Fri Dec 15 16:45:46 GMT 2023 , Edited by admin on Fri Dec 15 16:45:46 GMT 2023
PRIMARY Merck Index
CHEBI
34623
Created by admin on Fri Dec 15 16:45:46 GMT 2023 , Edited by admin on Fri Dec 15 16:45:46 GMT 2023
PRIMARY
EPA CompTox
DTXSID5023954
Created by admin on Fri Dec 15 16:45:46 GMT 2023 , Edited by admin on Fri Dec 15 16:45:46 GMT 2023
PRIMARY
NSC
8931
Created by admin on Fri Dec 15 16:45:46 GMT 2023 , Edited by admin on Fri Dec 15 16:45:46 GMT 2023
PRIMARY
WIKIPEDIA
CHLORDANE
Created by admin on Fri Dec 15 16:45:46 GMT 2023 , Edited by admin on Fri Dec 15 16:45:46 GMT 2023
PRIMARY
ALANWOOD
chlordane
Created by admin on Fri Dec 15 16:45:46 GMT 2023 , Edited by admin on Fri Dec 15 16:45:46 GMT 2023
PRIMARY
CAS
12789-03-6
Created by admin on Fri Dec 15 16:45:46 GMT 2023 , Edited by admin on Fri Dec 15 16:45:46 GMT 2023
NO STRUCTURE GIVEN
SMS_ID
100000125925
Created by admin on Fri Dec 15 16:45:46 GMT 2023 , Edited by admin on Fri Dec 15 16:45:46 GMT 2023
PRIMARY
HSDB
802
Created by admin on Fri Dec 15 16:45:46 GMT 2023 , Edited by admin on Fri Dec 15 16:45:46 GMT 2023
PRIMARY
CAS
57-74-9
Created by admin on Fri Dec 15 16:45:46 GMT 2023 , Edited by admin on Fri Dec 15 16:45:46 GMT 2023
PRIMARY
NCI_THESAURUS
C29814
Created by admin on Fri Dec 15 16:45:46 GMT 2023 , Edited by admin on Fri Dec 15 16:45:46 GMT 2023
PRIMARY
MESH
D002706
Created by admin on Fri Dec 15 16:45:46 GMT 2023 , Edited by admin on Fri Dec 15 16:45:46 GMT 2023
PRIMARY
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Related Record Type Details
METABOLITE -> PARENT
METABOLITE -> PARENT
Related Record Type Details
ACTIVE MOIETY
Definition References