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Details

Stereochemistry ACHIRAL
Molecular Formula C16H25N5O2
Molecular Weight 319.402
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MIDAXIFYLLINE

SMILES

CCCN1C2=C(NC(=N2)C3(N)CCCC3)C(=O)N(CCC)C1=O

InChI

InChIKey=UFOBUCDTKQDDTN-UHFFFAOYSA-N
InChI=1S/C16H25N5O2/c1-3-9-20-12-11(13(22)21(10-4-2)15(20)23)18-14(19-12)16(17)7-5-6-8-16/h3-10,17H2,1-2H3,(H,18,19)

HIDE SMILES / InChI

Description

Midaxifylline, a potent and selective xanthine adenosine A1 receptor antagonist, was investigated for the treatment of Alzheimer's disease, cardiovascular disorders, kidney disorders, and major depressive disorder. However, all studies were discontinued.

Originator

Approval Year

Unknown
139594
Name Type Language
MIDAXIFYLLINE
INN   WHO-DD  
INN  
Official Name English
8-(1-AMINOCYCLOPENTYL)-1,3-DIPROPYLXANTHINE
Systematic Name English
Midaxifylline [WHO-DD]
Common Name English
midaxifylline [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C744
Created by admin on Fri Dec 15 16:14:16 GMT 2023 , Edited by admin on Fri Dec 15 16:14:16 GMT 2023
NCI_THESAURUS C319
Created by admin on Fri Dec 15 16:14:16 GMT 2023 , Edited by admin on Fri Dec 15 16:14:16 GMT 2023
Code System Code Type Description
FDA UNII
A937Z0MS6C
Created by admin on Fri Dec 15 16:14:16 GMT 2023 , Edited by admin on Fri Dec 15 16:14:16 GMT 2023
PRIMARY
CAS
151159-23-8
Created by admin on Fri Dec 15 16:14:16 GMT 2023 , Edited by admin on Fri Dec 15 16:14:16 GMT 2023
PRIMARY
INN
7641
Created by admin on Fri Dec 15 16:14:16 GMT 2023 , Edited by admin on Fri Dec 15 16:14:16 GMT 2023
PRIMARY
PUBCHEM
3047747
Created by admin on Fri Dec 15 16:14:16 GMT 2023 , Edited by admin on Fri Dec 15 16:14:16 GMT 2023
PRIMARY
EVMPD
SUB03288MIG
Created by admin on Fri Dec 15 16:14:16 GMT 2023 , Edited by admin on Fri Dec 15 16:14:16 GMT 2023
PRIMARY
SMS_ID
100000085962
Created by admin on Fri Dec 15 16:14:16 GMT 2023 , Edited by admin on Fri Dec 15 16:14:16 GMT 2023
PRIMARY
ChEMBL
CHEMBL2106736
Created by admin on Fri Dec 15 16:14:16 GMT 2023 , Edited by admin on Fri Dec 15 16:14:16 GMT 2023
PRIMARY
EPA CompTox
DTXSID90164721
Created by admin on Fri Dec 15 16:14:16 GMT 2023 , Edited by admin on Fri Dec 15 16:14:16 GMT 2023
PRIMARY
NCI_THESAURUS
C66147
Created by admin on Fri Dec 15 16:14:16 GMT 2023 , Edited by admin on Fri Dec 15 16:14:16 GMT 2023
PRIMARY
ACTIVE MOIETY
Structure of MIDAXIFYLLINE
NIH
NCATS
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