GS-9148

Investigational

NC1=NC=NC2=C1N=CN2[C@@H]3O[C@H](OCP(O)(O)=O)C=C3F

InChIKey=MPSGQQOHTJUJKB-QUBYGPBYSA-N

InChI=1S/C10H11FN5O5P/c11-5-1-6(20-4-22(17,18)19)21-10(5)16-3-15-7-8(12)13-2-14-9(7)16/h1-3,6,10H,4H2,(H2,12,13,14)(H2,17,18,19)/t6-,10+/m0/s1

PubMed

Title	Date	PubMed
Design and profiling of GS-9148, a novel nucleotide analog active against nucleoside-resistant variants of human immunodeficiency virus type 1, and its orally bioavailable phosphonoamidate prodrug, GS-9131.	2008-02	18056282

Patents

Name

Type

Language

GS-9148

Code

English

GS9148

Preferred Name

English

PHOSPHONIC ACID, ((((2R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-FLUORO-2,5-DIHYDRO-2-FURANYL)OXY)METHYL)-

Systematic Name

English

PHOSPHONIC ACID, P-((((2R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-FLUORO-2,5-DIHYDRO-2-FURANYL)OXY)METHYL)-

Systematic Name

English

Code System Code Type Description

CAS

875608-25-6

Created by admin on Tue Apr 01 16:31:00 GMT 2025 , Edited by admin on Tue Apr 01 16:31:00 GMT 2025

PRIMARY

FDA UNII

A8OH1KW2TZ

Created by admin on Tue Apr 01 16:31:00 GMT 2025 , Edited by admin on Tue Apr 01 16:31:00 GMT 2025

PRIMARY

PUBCHEM

15958718

Created by admin on Tue Apr 01 16:31:00 GMT 2025 , Edited by admin on Tue Apr 01 16:31:00 GMT 2025

PRIMARY

ACTIVE MOIETY


					A8OH1KW2TZ

GS-9148

PRODRUG (METABOLITE ACTIVE)


					U8S0IC8DY7