ROVAFOVIR ETALAFENAMIDE

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H24FN6O6P
Molecular Weight	506.424
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC(=O)[C@H](C)N[P@@](=O)(CO[C@H]1O[C@@H](N2C=NC3=C2N=CN=C3N)C(F)=C1)OC4=CC=CC=C4

InChI

InChIKey=OCJRRXHWPBXZSU-BJBBEUPESA-N

InChI=1S/C21H24FN6O6P/c1-3-31-21(29)13(2)27-35(30,34-14-7-5-4-6-8-14)12-32-16-9-15(22)20(33-16)28-11-26-17-18(23)24-10-25-19(17)28/h4-11,13,16,20H,3,12H2,1-2H3,(H,27,30)(H2,23,24,25)/t13-,16-,20+,35+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C21H24FN6O6P
Molecular Weight	506.424
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Design and profiling of GS-9148, a novel nucleotide analog active against nucleoside-resistant variants of human immunodeficiency virus type 1, and its orally bioavailable phosphonoamidate prodrug, GS-9131.	2008-02	18056282

Patents

Substance Class	Chemical Created by `admin` on `Tue Apr 01 16:30:59 GMT 2025` Edited by `admin` on `Tue Apr 01 16:30:59 GMT 2025`
Record UNII	U8S0IC8DY7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ROVAFOVIR ETALAFENAMIDE

Official Name

English

GS-9131

Preferred Name

English

ROVAFOVIR ETALAFENAMIDE [USAN]

Common Name

English

GS9131

Code

English

rovafovir etalafenamide [INN]

Common Name

English

L-ALANINE, N-((S)-((((2R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-FLUORO-2,5-DIHYDRO-2-FURANYL)OXY)METHYL)PHENOXYPHOSPHINYL)-, ETHYL ESTER

Systematic Name

English

GS-9148 PHOSPHONOAMIDATE PRODRUG

Code

English

Code System Code Type Description

USAN

HI-11