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Details

Stereochemistry RACEMIC
Molecular Formula C10H13NO4
Molecular Weight 211.2145
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LISADIMATE

SMILES

NC1=CC=C(C=C1)C(=O)OCC(O)CO

InChI

InChIKey=WHQOKFZWSDOTQP-UHFFFAOYSA-N
InChI=1S/C10H13NO4/c11-8-3-1-7(2-4-8)10(14)15-6-9(13)5-12/h1-4,9,12-13H,5-6,11H2

HIDE SMILES / InChI

Description

Lisadimate (glyceryl PABA), a substituted aminobenzoate, is a sunscreen with actions similar to those of aminobenzoic acid. It is effective against UVB light. Glyceryl PABA (Escalol 106), present in many popular sunscreens, is a common sensitizer which invariably cross-reacts with benzocaine; it is present in over 400 over-the-counter products. Glyceryl PABA does not appear to cross-react with the sunscreening agents amyl (Escalol 506) and octyl (Escalol 507) dimethyl PABA. Glyceryl PABA, may, on occasion, cross-react with para-aminobenzoic acid (PABA), paraphenylenediamine, aniline, and sulfa drugs. Ironically, the sunscreening agent glyceryl PABA may, itself, act as a photosensitizing agent.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
Unknown

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
Sunscreen products containing lisadimate should be applied 1 to 2 hours before sun exposure.
Route of Administration: Topical
In Vitro Use Guide
Unknown