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Details

Stereochemistry MIXED
Molecular Formula C18H24I3N3O8
Molecular Weight 791.1119
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of IOXILAN

SMILES

CC(=O)N(CC(O)CO)C1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)NCCO)=C1I

InChI

InChIKey=UUMLTINZBQPNGF-UHFFFAOYSA-N
InChI=1S/C18H24I3N3O8/c1-8(28)24(5-10(30)7-27)16-14(20)11(17(31)22-2-3-25)13(19)12(15(16)21)18(32)23-4-9(29)6-26/h9-10,25-27,29-30H,2-7H2,1H3,(H,22,31)(H,23,32)

HIDE SMILES / InChI

Description

Ioxilan is a nonionic X-ray contrast agent approved by the United States Food and Drug Administration for X-ray imaging contrast enhancement. Ioxilan can be administered intravenously for excretory urography and contrast-enhanced computed tomography (CT) imaging of the head and body. Ioxilan can also be given intraarterially for cerebral arteriograpy, coronary arteriography and left ventriculography, visceral angiography, aortography, and peripheral arteriography.

CNS Activity

Originator

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
OXILAN-300

T1/2

ValueDoseCo-administeredAnalytePopulation
13.1 min
72.8 g single, intravascular
IOXILAN plasma
Homo sapiens
23.5 min
72.8 g single, intravascular
IOXILAN plasma
Homo sapiens

Funbound

ValueDoseCo-administeredAnalytePopulation
100%
72.8 g single, intravascular
IOXILAN plasma
Homo sapiens
100%
72.8 g single, intravascular
IOXILAN plasma
Homo sapiens

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
300 mgI/mL or 350 mgI/mL injection
Route of Administration: Other
In Vitro Use Guide
Unknown